ArticleAmerican journal of respiratory and critical care medicine2022
Hereditary Mucin Deficiency Caused by Biallelic Loss of Function of
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In one paragraph
Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 26 citations in OpenAlex.
- MUC5B and MUC5AC function in combination to regulate mucociliary transport on human airway epithelium.bioRxiv : the preprint server for biology · 2026Article
- Interstitial Lung Disease in Children: Rare Genetic Variants Beyond Surfactant Dysfunction.Pediatric pulmonology · 2026Article
- Telomere dysfunction and mucociliary impairment drive idiopathic pulmonary fibrosis susceptibility: insights from a Sardinian whole-exome study.BMJ open respiratory research · 2026Article
- Airway secretory cells contain both a perinuclear Golgi ribbon and dispersed Golgi satellites.American journal of respiratory cell and molecular biology · 2026Article
- Obstructive fibrinous tracheal pseudomembrane complicated with bronchial mucus plug: A rare post-intubation complication case report.Journal of anesthesia and translational medicine · 2026Article
- Interstitial lung disease and the STING pathway.The Journal of clinical investigation · 2026Review
- Loss of RPGR disrupts motile cilia and causes primary ciliary dyskinesia by affecting F-actin dynamics.The Journal of clinical investigation · 2026Article
- Comparison of airway mucin 5AC and 5B expression in preterm-born adults and asthma.ERJ open research · 2026Article
- Airway Mucosal Defense: Mucins, Innate Immunity, and Contemporary Mucoactive Strategies.Biomedicines · 2026Review
- Genetic investigation of sinopulmonary diseases in Vietnam: seeking specific causes from non-specific symptoms.Orphanet journal of rare diseases · 2025Article
- A Computable Electronic Health Record ARDS Classifier and the Association Between theCHEST critical care · 2025Article
- Liquiritin Suppresses Intracellular and Secreted MUC5AC and MUC5B in Human Airway Epithelial Cells.International journal of molecular sciences · 2025Article
- Mucins and Their Roles in Asthma.Immunological reviews · 2025Review
- Progressive lung fibrosis: reprogramming a genetically vulnerable bronchoalveolar epithelium.The Journal of clinical investigation · 2025Review
- Pulmonary-delivered Anticalin Jagged-1 antagonists reduce experimental airway mucus hyperproduction and obstruction.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Immune activation and mucin dysregulation in pediatric refractoryFrontiers in cellular and infection microbiology · 2025Article
- Expression Levels of MUC5AC and MUC5B in Airway Goblet Cells Are Associated with Traits of COPD and Progression of Chronic Airflow Limitation.International journal of molecular sciences · 2024Article
- Imperfect wound healing sets the stage for chronic diseases.Science (New York, N.Y.) · 2024Review
- Emerging cell and molecular targets for treating mucus hypersecretion in asthma.Allergology international : official journal of the Japanese Society of Allergology · 2024Review
- MUC5AC Genetic Variation Is Associated With Tuberculous Meningitis Cerebral Spinal Fluid Cytokine Responses and Mortality.The Journal of infectious diseases · 2023Article
Corrections and comments
- Commented on byThe Mucin Gene2022
Authors and funding
19 authors at 10 institutions in 6 countries.
Gregory CostainDivision of Clinical and Metabolic Genetics.
Zhen LiuGenetics and Genome Biology, Research Institute.
Vito MennellaClinical & Experimental Sciences Academic Unit Biomedical Research Center, National Health Research Institute, University of Southampton, Southampton, United Kingdom.
Giorgia RadicioniMarsico Lung Institute.
Adrienn N GocziCell Biology Program.
Alexandra AlbulescuCell Biology Program.
Susan WalkerGenetics and Genome Biology, Research Institute.
Bo NganDivision of Pathology, Department of Paediatric Laboratory Medicine.
David MansonDepartment of Diagnostic Imaging.
Reza ValiDepartment of Diagnostic Imaging.
Meraj KhanTranslational Medicine, Research Institute.
Nades PalaniyarTranslational Medicine, Research Institute.
David B HillMarsico Lung Institute.
David A HallDepartment of Medicine, and.
Christian R MarshallThe Centre for Applied Genomics.
Michael KnowlesMarsico Lung Institute.
Maimoona A ZariwalaMarsico Lung Institute.
Mehmet KesimerMarsico Lung Institute.
Sharon D DellChild Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0003-2169-9407
Lung Institute · USTranslational Research Institute · AUGenomics (United Kingdom) · GBGenomix Biotech (India) · INHong Kong University of Science and Technology · HKNIHR Southampton Respiratory Biomedical Research Unit · GBPediatrics and Genetics · USSt. Michael's Hospital · CAUniversity of British Columbia · CAUniversity of North Carolina at Chapel Hill · US
Funding
The Impact of COVID-19 on People Living with Rare Diseases and Their FamiliesU2CTR002818 · NCATS · CINCINNATI CHILDRENS HOSP MED CTR · PI Maurizio Macaluso, Michael Wagner · 2019 to 2026
$51.2MVector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Scott H Randell · 2004 to 2026
$26.5MLongitudinal Characterization of Respiratory Tract Exacerbations and Treatment Responses in Primary Ciliary DyskinesiaU54HL096458 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI OLIVIER, KENNETH N. · 2009 to 2023
$20.0MPathogenesis of PCD Lung DiseaseR01HL071798 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KNOWLES, MICHAEL R · 2004 to 2021
$7.2MThe role of mucin-protein interactions in the innate defense of the lungR01HL103940 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KESIMER, MEHMET · 2010 to 2014
$1.8MAirway mucus/mucin composition and proteome in COPD: A SPIROMICS ancillary studyR01HL110906 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KESIMER, MEHMET · 2011 to 2014
$1.4MMedical Research Council MC_UU_00025/13NCATS NIH HHS U2C TR002818NHLBI NIH HHS R01 HL071798NHLBI NIH HHS R01 HL103940NHLBI NIH HHS R01 HL110906NHLBI NIH HHS U54 HL096458NHLBI NIH HHS U54HL096458NIDDK NIH HHS P30 DK065988
Abstract
PubMed holds no abstract for this paper.
Indexed as
Lung DiseasesMucinsAdultAnimalsFemaleHumansLungMiceMucin 5ACMucin-5BMucociliary ClearanceMucusMUC5B protein, humanMuc5b protein, mouseMucin 5ACMucin-5BMucinsbronchiectasisMUC5Bmucociliary clearance
Identifiers
What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.