Evidence map›Paper›PMID 35026949›Full record

ArticleThe journal of physical chemistry. B2022

Computational and Experimental Characterization of rDNA and rRNA G-Quadruplexes.

Adam T Green, Amanda J Pickard, Rongzhong Li, Alexander D MacKerell, Ulrich Bierbach, Samuel S Cho

Open access · greenAbstract read
In one paragraph

Article in The journal of physical chemistry. B, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. G-quadruplex stabilization induces DNA breaks in pericentromeric repetitive DNA sequences in B lymphocytes.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Adam T GreenDepartment of Physics, Wake Forest University, Winston-Salem, North Carolina 27109, United States.
Amanda J PickardDepartment of Chemistry, Wake Forest University, Wake Downtown Campus, Winston-Salem, North Carolina 27101, United States.
Rongzhong LiDepartment of Physics, Wake Forest University, Winston-Salem, North Carolina 27109, United States.
Alexander D MacKerellDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, United States.ORCID 0000-0001-8287-6804
Ulrich BierbachDepartment of Chemistry, Wake Forest University, Wake Downtown Campus, Winston-Salem, North Carolina 27101, United States.ORCID 0000-0001-5658-7662
Samuel S ChoDepartment of Physics, Wake Forest University, Winston-Salem, North Carolina 27109, United States.ORCID 0000-0002-6113-135X
Wake Forest University · USUniversity of Maryland, Baltimore · US

Funding

Macromolecular Conformational HeterogeneityR35GM131710 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI ALEXANDER D MACKERELL · 2019 to 2026
$6.2M
NIGMS NIH HHS R35 GM131710
6 · The paper itself

Abstract

DNA G-quadruplexes in human telomeres and gene promoters are being extensively studied for their role in controlling the growth of cancer cells. G-quadruplexes have been unambiguously shown to exist both

Indexed as

G-QuadruplexesDNA, RibosomalHumansMolecular Dynamics SimulationRNA, RibosomalTelomereDNA, RibosomalRNA, Ribosomal

Identifiers

PMID35026949
PMCPMC8995076
OpenAlexW4206456227

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.