Evidence map›Paper›PMID 35027372›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

In Vivo Evaluation of 6 Analogs of

Jae-Hoon Lee, Fabrice G Siméon, Jeih-San Liow, Cheryl L Morse, Robert L Gladding, Jose A Montero Santamaria, Ioline D Henter, Sami S Zoghbi, Victor W Pike, Robert B Innis

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Neuroinflammation demonstrated byAlzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
  3. Radiopharmaceuticals and their applications in medicine.Signal transduction and targeted therapy · 2025
    Review
  4. TSPO Radioligands for Neuroinflammation: An Overview.Molecules (Basel, Switzerland) · 2024
    Review
  5. Review
  6. In vivo evaluation of a novelEuropean journal of nuclear medicine and molecular imaging · 2023
    Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Jae-Hoon LeeMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland; and jae-hoon.lee@nih.gov.
Fabrice G SiméonMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland; and.
Jeih-San LiowMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland; and.
Cheryl L MorseMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland; and.
Robert L GladdingMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland; and.
Jose A Montero SantamariaMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland; and.
Ioline D HenterMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland; and.
Sami S ZoghbiMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland; and.
Victor W PikeMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland; and.
Robert B InnisMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland; and.
National Institutes of Health · USNational Institute of Mental Health · US

Funding

PET Radiopharmaceutical SciencesZIAMH002793 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PIKE, VICTOR W · 2009 to 2025
$69.8M
Translational Evaluation Of PET RadiotracersZIAMH002795 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$32.0M
6 · The paper itself

Abstract

Because of its excellent ratio of specific to nondisplaceable uptake, the radioligand

Indexed as

FluorineReceptors, GABABrainCarbon RadioisotopesHumansPositron-Emission TomographyQuinazolinesRadiopharmaceuticals(11)C-ER176Carbon RadioisotopesFluorineQuinazolinesRadiopharmaceuticalsReceptors, GABATSPO protein, humanneuroinflammationPETradiometabolitesspecific-to-nondisplaceable uptaketranslocator protein

Identifiers

PMID35027372
PMCPMC9364345
OpenAlexW4206680552

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.