Evidence map›Paper›PMID 35030062›Full record

ReviewAnnals of the American Thoracic Society2022

Asthma in the Americas: An Update: A Joint Perspective from the Brazilian Thoracic Society, Canadian Thoracic Society, Latin American Thoracic Society, and American Thoracic Society.

Erick Forno, Diego D Brandenburg, Jose A Castro-Rodriguez, Carlos A Celis-Preciado, Fernando Holguin, Christopher Licskai, Stephanie Lovinsky-Desir, Marcia Pizzichini, Alejandro Teper, Connie Yang and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in Annals of the American Thoracic Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. The pitfalls of evaluating asthma control in children and adolescents.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Article
  6. Pulmonary arterial hypertension in Latin America. The age and comorbidity paradox.International journal of cardiology. Congenital heart disease · 2025
    Review
  7. Review
  8. Serum 17Frontiers in immunology · 2025
    Article
  9. Thoracic mobility in school-aged asthmatic children.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2025
    Article
  10. Article
  11. Emerging cell and molecular targets for treating mucus hypersecretion in asthma.Allergology international : official journal of the Japanese Society of Allergology · 2024
    Review
  12. Article
  13. Article
  14. Social determinants of respiratory health from birth: still of concern in the 21st century?European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  15. Article
  16. Asthma in the Brazilian Unified Health Care System: an epidemiological analysis from 2008 to 2021.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024
    Article
  17. Article
  18. Asthma and Chronic Obstructive Pulmonary Disease.Clinics in chest medicine · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 6 countries.

Erick FornoDivision of Pediatric Pulmonary Medicine, University of Pittsburgh School of Medicine and Pediatric Asthma Center, University of Pittsburgh Medical Center Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0001-6497-9885
Diego D BrandenburgDepartment of Pediatrics, Pediatric Pulmonology Unit, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.
Jose A Castro-RodriguezDepartment of Pediatric Pulmonology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Carlos A Celis-PreciadoPulmonary Unit, Internal Medicine Department, Hospital Universitario San Ignacio and Faculty of Medicine, Pontificia Universidad Javeriana, Bogota, Colombia.ORCID 0000-0001-8405-4513
Fernando HolguinDivision of Pulmonary Sciences and Critical Care, University of Colorado Denver, Denver, Colorado.
Christopher LicskaiDepartment of Medicine, Western University Canada, Schulich School of Medicine and Dentistry, London Health Sciences Centre, London, Ontario, Canada.
Stephanie Lovinsky-DesirDivision of Pediatric Pulmonary Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0003-2272-4387
Marcia PizzichiniPost-Graduate Program of Medical Sciences, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil.
Alejandro TeperRespiratory Center, Hospital de Niños Dr. Ricardo Gutiérrez, Ciudad Autónoma de Buenos Aires, Argentina; and.
Connie YangDivision of Respiratory Medicine, University of British Columbia, British Columbia Children's Hospital, Vancouver, British Columbia, Canada.
Juan C CeledónDivision of Pediatric Pulmonary Medicine, University of Pittsburgh School of Medicine and Pediatric Asthma Center, University of Pittsburgh Medical Center Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0002-6139-5320
Children's Hospital of Pittsburgh · USBritish Columbia Children's Hospital · CAColumbia University Irving Medical Center · USHospital de Clínicas de Porto Alegre · BRHospital General de Niños Ricardo Gutierrez · ARHospital Universitario San Ignacio · COPontificia Universidad Católica de Chile · CLUniversidade Federal de Santa Catarina · BRUniversity of Colorado Denver · USWestern University · CA

Funding

Epigenetic Variation and Childhood Asthma in Puerto RicansR01HL117191 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2013 to 2020
$5.8M
Genes, Home Allergens and Asthma Puerto Rican ChildrenR01HL079966 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2006 to 2010
$3.8M
Nasal epithelial epigenomics and transcriptomics and asthma in Hispanic adultsR01HL152475 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS, ISASI, CARMEN R. · 2021 to 2025
$3.4M
Obesity and Childhood Asthma: The Role of Adipose TissueR01HL149693 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FORNO, ERICK · 2020 to 2024
$3.0M
Exposure to violence, epigenetic variation, and asthma in Puerto Rican childrenR01MD011764 · NIMHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2017 to 2020
$1.3M
NHLBI NIH HHS R01 HL079966NHLBI NIH HHS R01 HL117191NHLBI NIH HHS R01 HL149693NHLBI NIH HHS R01 HL152475NIMHD NIH HHS R01 MD011764
6 · The paper itself

Abstract

Asthma affects a large number of people living in the Americas, a vast and diverse geographic region comprising 35 nations in the Caribbean and North, Central, and South America. The marked variability in the prevalence, morbidity, and mortality from asthma across and within nations in the Americas offers a unique opportunity to improve our understanding of the risk factors and management of asthma phenotypes and endotypes in children and adults. Moreover, a better assessment of the causes and treatment of asthma in less economically developed regions in the Americas would help diagnose and treat individuals migrating from those areas to Canada and the United States. In this focused review, we first assess the epidemiology of asthma, review known and potential risk factors, and examine commonalities and differences in asthma management across the Americas. We then discuss future directions in research and health policies to improve the prevention, diagnosis, and management of pediatric and adult asthma in the Americas, including standardized and periodic assessment of asthma burden across the region; large-scale longitudinal studies including omics and comprehensive environmental data on racially and ethnically diverse populations; and dissemination and implementation of guidelines for asthma management across the spectrum of disease severity. New initiatives should recognize differences in socioeconomic development and health care systems across the region while paying particular attention to novel or more impactful risk factors for asthma in the Americas, including indoor pollutants such as biomass fuel, tobacco use, infectious agents and the microbiome, and psychosocial stressor and chronic stress.

Indexed as

AsthmaAmericasBrazilCanadaChildHumansLatin AmericaUnited StatesAmericasasthmarisk factorstreatment

Identifiers

PMID35030062
PMCPMC8996271
OpenAlexW4205790847

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.