Evidence map›Paper›PMID 35032089›Full record

ArticleChemphyschem : a European journal of chemical physics and physical chemistry2022

Investigating Membrane-Mediated Antimicrobial Peptide Interactions with Synchrotron Radiation Far-Infrared Spectroscopy.

Andrea Hornemann, Diane M Eichert, Arne Hoehl, Brigitte Tiersch, Gerhard Ulm, Maxim G Ryadnov, Burkhard Beckhoff

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemphyschem : a European journal of chemical physics and physical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Investigating Membrane-Mediated Antimicrobial Peptide Interactions with Synchrotron Radiation Far-Infrared Spectroscopy.Chemphyschem : a European journal of chemical physics and physical chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Andrea HornemannDepartment 7.1 Radiometry with Synchrotron Radiation and, Department 7.2 X-Ray Metrology with Synchrotron Radiation, Physikalisch-Technische Bundesanstalt (PTB), Abbestr. 2-12, 10587, Berlin, Germany.ORCID 0000-0002-0945-1508
Diane M EichertELETTRA - Sincrotrone Trieste, S.S.14 Km 163.5 in Area Science Park, 34149, Basovizza, Trieste, Italy.ORCID 0000-0003-4173-2120
Arne HoehlDepartment 7.1 Radiometry with Synchrotron Radiation and, Department 7.2 X-Ray Metrology with Synchrotron Radiation, Physikalisch-Technische Bundesanstalt (PTB), Abbestr. 2-12, 10587, Berlin, Germany.ORCID 0000-0003-0813-7514
Brigitte TierschUniversität Potsdam, Karl-Liebknecht-Str. 24-25, 14476, Potsdam, Germany.ORCID 0000-0001-7014-3478
Gerhard UlmDepartment 7.1 Radiometry with Synchrotron Radiation and, Department 7.2 X-Ray Metrology with Synchrotron Radiation, Physikalisch-Technische Bundesanstalt (PTB), Abbestr. 2-12, 10587, Berlin, Germany.
Maxim G RyadnovNational Physical Laboratory, Hampton Rd, Teddington, Middlesex, TW11 0LW, UK.ORCID 0000-0003-4847-1154
Burkhard BeckhoffDepartment 7.1 Radiometry with Synchrotron Radiation and, Department 7.2 X-Ray Metrology with Synchrotron Radiation, Physikalisch-Technische Bundesanstalt (PTB), Abbestr. 2-12, 10587, Berlin, Germany.
Physikalisch-Technische Bundesanstalt · DEElettra-Sincrotrone Trieste S.C.p.A. · ITNational Physical Laboratory · GBUniversity of Potsdam · DE

Funding

EURAMETEURAMET 217257EURAMET joint research projectEuropean Community's Seventh Framework Programme, ERA-NET Plus 217257Helmholtz-Zentrum Berlin (HZB)
6 · The paper itself

Abstract

Synchrotron radiation-based Fourier transform infrared spectroscopy enables access to vibrational information from mid over far infrared to even terahertz domains. This information may prove critical for the elucidation of fundamental bio-molecular phenomena including folding-mediated innate host defence mechanisms. Antimicrobial peptides (AMPs) represent one of such phenomena. These are major effector molecules of the innate immune system, which favour attack on microbial membranes. AMPs recognise and bind to the membranes whereupon they assemble into pores or channels destabilising the membranes leading to cell death. However, specific molecular interactions responsible for antimicrobial activities have yet to be fully understood. Herein we probe such interactions by assessing molecular specific variations in the near-THz 400-40 cm

Indexed as

Antimicrobial PeptidesSynchrotronsAntimicrobial Cationic PeptidesSpectrophotometry, InfraredSpectroscopy, Fourier Transform InfraredAntimicrobial Cationic PeptidesAntimicrobial Peptidesantimicrobial peptideselectrostatic interactionsIR spectroscopyphospholipid membranesprotein folding

Identifiers

PMID35032089
PMCPMC9303692
OpenAlexW4205686676

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.