Evidence map›Paper›PMID 35038899›Full record

ArticlemBio2022

Unmasking of CgYor1-Dependent Azole Resistance Mediated by Target of Rapamycin (TOR) and Calcineurin Signaling in Candida glabrata.

Sonam Kumari, Mohit Kumar, Brooke D Esquivel, Mohd Wasi, Ajay Kumar Pandey, Nitesh Kumar Khandelwal, Alok K Mondal, Theodore C White, Rajendra Prasad, Naseem A Gaur

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Evolutionary accumulation ofEmerging microbes & infections · 2024
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Sonam KumariYeast Biofuel Group, International Centre for Genetic Engineering and Biotechnologygrid.425195.e, New Delhi, India.
Mohit KumarYeast Biofuel Group, International Centre for Genetic Engineering and Biotechnologygrid.425195.e, New Delhi, India.
Brooke D EsquivelSchool of Biological and Chemical Sciences, University of Missouri at Kansas City, Kansas City, Missouri, USA.ORCID 0000-0001-7328-4057
Mohd WasiSchool of Life Sciences, Jawaharlal Nehru Universitygrid.10706.30, New Delhi, India.
Ajay Kumar PandeyYeast Biofuel Group, International Centre for Genetic Engineering and Biotechnologygrid.425195.e, New Delhi, India.
Nitesh Kumar KhandelwalYeast Biofuel Group, International Centre for Genetic Engineering and Biotechnologygrid.425195.e, New Delhi, India.
Alok K MondalSchool of Life Sciences, Jawaharlal Nehru Universitygrid.10706.30, New Delhi, India.
Theodore C WhiteSchool of Biological and Chemical Sciences, University of Missouri at Kansas City, Kansas City, Missouri, USA.
Rajendra PrasadAmity Institute of Biotechnology and Integrative Science and Health, Amity University Gurgaon, Haryana, India.
Naseem A GaurYeast Biofuel Group, International Centre for Genetic Engineering and Biotechnologygrid.425195.e, New Delhi, India.
International Centre for Genetic Engineering and Biotechnology · INJawaharlal Nehru University · INUniversity of Missouri–Kansas City · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, 18 predicted membrane-localized ABC transporters of Candida glabrata were deleted individually to create a minilibrary of knockouts (KO). The transporter KOs were analyzed for their susceptibility toward antimycotic drugs. Although Cg

Indexed as

AzolesCandidiasisAntifungal AgentsATP-Binding Cassette TransportersCalcineurinCandida glabrataDrug Resistance, FungalFluconazoleFungal ProteinsMembrane Transport ProteinsMicrobial Sensitivity TestsNitrogenOligomycinsSirolimusAntifungal AgentsATP-Binding Cassette TransportersAzolesCalcineurinFluconazoleFungal ProteinsMembrane Transport ProteinsNitrogenOligomycinsSirolimusABC transportersazole drug resistancecalcineurinCandida glabrataTOR pathway

Identifiers

PMID35038899
PMCPMC8764518
OpenAlexW4206513382

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.