Evidence map›Paper›PMID 35045840›Full record

ArticleBMC medical informatics and decision making2022

Machine learning model for predicting acute kidney injury progression in critically ill patients.

Canzheng Wei, Lifan Zhang, Yunxia Feng, Aijia Ma, Yan Kang

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Canzheng Wei *Department of Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, 610041, China.
Lifan Zhang *Department of Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, 610041, China.
Yunxia FengDepartment of Nephrology, Mianyan Central Hospital, University of Electronic Science and Technology of China, Chengdu, 621000, China.
Aijia MaDepartment of Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, 610041, China.
Yan KangDepartment of Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, 610041, China. Kangyan@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is a serve and harmful syndrome in the intensive care unit. Comparing to the patients with AKI stage 1/2, the patients with AKI stage 3 have higher in-hospital mortality and risk of progression to chronic kidney disease. The purpose of this study is to develop a prediction model that predict whether patients with AKI stage 1/2 will progress to AKI stage 3.

methodsPatients with AKI stage 1/2, when they were first diagnosed with AKI in the Medical Information Mart for Intensive Care, were included. We used the Logistic regression and machine learning extreme gradient boosting (XGBoost) to build two models which can predict patients who will progress to AKI stage 3. Established models were evaluated by cross-validation, receiver operating characteristic curve, and precision-recall curves.

resultsWe included 25,711 patients, of whom 2130 (8.3%) progressed to AKI stage 3. Creatinine, multiple organ failure syndromes were the most important in AKI progression prediction. The XGBoost model has a better performance than the Logistic regression model on predicting AKI stage 3 progression. Thus, we build a software based on our data which can predict AKI progression in real time.

conclusionsThe XGboost model can better identify patients with AKI progression than Logistic regression model. Machine learning techniques may improve predictive modeling in medical research.

Indexed as

Acute Kidney InjuryCritical IllnessHumansIntensive Care UnitsLogistic ModelsMachine LearningROC CurveAcute kidney injuryCritical careExtreme gradient boostingLogistic Models

Identifiers

PMID35045840
PMCPMC8772216

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.