Evidence map›Paper›PMID 35052234›Full record

ArticleHealthcare (Basel, Switzerland)2021

HIV Viral Suppression among People Living with HIV on Antiretroviral Therapy in Haut-Katanga and Kinshasa Provinces of Democratic Republic of Congo.

Gulzar H Shah, Lievain Maluantesa, Gina D Etheredge, Kristie C Waterfield, Osaremhen Ikhile, Roger Beni, Elodie Engetele, Astrid Mulenga

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gulzar H ShahJiann-Ping Hsu College of Public Health, Georgia Southern University, Statesboro, GA 30460, USA.ORCID 0000-0003-0954-3418
Lievain MaluantesaFHI 360 Congo, Kinshasa, Congo.ORCID 0000-0002-1712-4400
Gina D EtheredgeFHI 360, Washington, DC 20009, USA.
Kristie C WaterfieldDepartment of Interdisciplinary Healthcare, University of North Georgia, Dahlonega, GA 30597, USA.
Osaremhen IkhileJiann-Ping Hsu College of Public Health, Georgia Southern University, Statesboro, GA 30460, USA.ORCID 0000-0002-9887-1546
Roger BeniNational AIDS Control Program (PNLS), HIV Program, Ministry of Health, Kinshasa, Congo.
Elodie EngeteleFHI 360 Congo, Kinshasa, Congo.
Astrid MulengaFHI 360 Congo, Kinshasa, Congo.

Funding

CDC HHS 5NU2GGH002033-02-00
6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) infections and less-than-optimal care of people living with HIV (PLHIV) continue to challenge public health and clinical care organizations in the communities that are most impacted by HIV. In the era of evidence-based public health, it is imperative to monitor viral load (VL) in PLHIV according to global and national guidelines and assess the factors associated with variation in VL levels. PURPOSE: This study had two objectives-(a) to describe the levels of HIV VL in persons on antiretroviral therapy (ART), and (b) to analyze the significance of variation in VL by patients' demographic and clinical characteristics, outcomes of HIV care, and geographic characteristics of HIV care facilities.

methodsThe study population for this quantitative study was 49,460 PLHIV in the Democratic Republic of Congo (DRC) receiving ART from 241 CDC-funded HIV/AIDS clinics in the Haut-Katanga and Kinshasa provinces of the DRC. Analysis of variance (ANOVA) was performed, including Tamhane's T2 test for pairwise comparisons using de-identified data on all patients enrolled in the system by the time the data were extracted for this study by the HIV programs in May 2019.

resultsThe VL was undetectable (<40 copies/mL) for 56.4% of the patients and 24.7% had VL between 40 copies/mL and less than 1000 copies per mL, indicating that overall, 81% had VL < 1000 and were virologically suppressed. The remaining 19% had a VL of 1000 copies/mL or higher. The mean VL was significantly (

conclusionsThe VL was >1000 copies/mL for 19% of PLHIV receiving ART, indicating that these CDC-funded clinics and programs in the Haut-Katanga and Kinshasa provinces of DRC have more work to do. Strategically designed innovations in services are desirable, with customized approaches targeting PLHIV who are younger, male, those LTFU, with HIV/TB co-infection, and those receiving care from urban clinics.

Indexed as

antiretroviral therapyDemocratic Republic of CongoHIV viral load suppressionTB/HIV co-infectionWHO clinical stages

Identifiers

PMID35052234
PMCPMC8775118

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.