Evidence map›Paper›PMID 35053232›Full record

ReviewBiomolecules2022

A Comprehensive Review of Receptor-Type Tyrosine-Protein Phosphatase Gamma (PTPRG) Role in Health and Non-Neoplastic Disease.

Christian Boni, Carlo Laudanna, Claudio Sorio

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Christian BoniDepartment of Medicine, General Pathology Division, University of Verona, 37134 Verona, Italy.ORCID 0000-0002-9982-4100
Carlo LaudannaDepartment of Medicine, General Pathology Division, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-4050-1056
Claudio SorioDepartment of Medicine, General Pathology Division, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-2739-4014
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein tyrosine phosphatase receptor gamma (PTPRG) is known to interact with and regulate several tyrosine kinases, exerting a tumor suppressor role in several type of cancers. Its wide expression in human tissues compared to the other component of group 5 of receptor phosphatases, PTPRZ expressed as a chondroitin sulfate proteoglycan in the central nervous system, has raised interest in its role as a possible regulatory switch of cell signaling processes. Indeed, a carbonic anhydrase-like domain (CAH) and a fibronectin type III domain are present in the N-terminal portion and were found to be associated with its role as [HCO

Indexed as

Signal TransductionBiomarkersCell AdhesionHumansOrgan SpecificityReceptor-Like Protein Tyrosine Phosphatases, Class 5Tumor Suppressor ProteinsBiomarkersPTPRG protein, humanReceptor-Like Protein Tyrosine Phosphatases, Class 5Tumor Suppressor ProteinsadhesionAlzheimer diseasecentral nervous systemHCO3− sensorinflammationinteraction networkneuropsychiatric disordersphosphatasePTPRGschizophrenia

Identifiers

PMID35053232
PMCPMC8773835
OpenAlexW4205215106

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.