Evidence map›Paper›PMID 35053318›Full record

ReviewCells2022

Oxysterols in the Immune Response to Bacterial and Viral Infections.

Cheng Xiang Foo, Stacey Bartlett, Katharina Ronacher

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Activation of GScience advances · 2026
    Article
  2. Review
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  4. GPR183 contributes to renal macrophage infiltration and fibrosis in kidney injury.American journal of physiology. Renal physiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Cheng Xiang FooTranslational Research Institute, Mater Research Institute, The University of Queensland, Brisbane, QLD 4102, Australia.ORCID 0000-0002-7539-7116
Stacey BartlettTranslational Research Institute, Mater Research Institute, The University of Queensland, Brisbane, QLD 4102, Australia.
Katharina RonacherTranslational Research Institute, Mater Research Institute, The University of Queensland, Brisbane, QLD 4102, Australia.ORCID 0000-0002-6371-1462
Translational Research Institute · AU

Funding

Altered immune-endocrine axis in type 2 diabetes and tuberculosis riskR01AI116039 · NIAID · STELLENBOSCH UNIVERSITY · PI KLEYNHANS, LEANIE, RESTREPO, BLANCA I · 2015 to 2019
$1.7M
NIAID NIH HHS R01 AI116039NIH HHS R01 AI116039
6 · The paper itself

Abstract

Oxidized cholesterols, the so-called oxysterols, are widely known to regulate cholesterol homeostasis. However, more recently oxysterols have emerged as important lipid mediators in the response to both bacterial and viral infections. This review summarizes our current knowledge of selected oxysterols and their receptors in the control of intracellular bacterial growth as well as viral entry into the host cell and viral replication. Lastly, we briefly discuss the potential of oxysterols and their receptors as drug targets for infectious and inflammatory diseases.

Indexed as

AnimalsBacterial InfectionsHumansOxysterolsVirus DiseasesOxysterols25-hydroxycholesterol7α,25-dihydroxycholesterolbacteriacholesterol 25 hydroxylaseGPR183infectionM. tuberculosisoxidized cholesteroloxysterolsSARS-CoV-2virus

Identifiers

PMID35053318
PMCPMC8773517
OpenAlexW4205674563

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.