Evidence mapPaperPMID 35053620Full record

ArticleCancers2022

HELLS Is Negatively Regulated by Wild-Type P53 in Liver Cancer by a Mechanism Involving P21 and FOXM1.

Stefanie Schuller, Jan Sieker, Philip Riemenschneider, Bianca Köhler, Elisabeth Drucker, Sofia M E Weiler, Daniel Dauch, Carsten Sticht, Benjamin Goeppert, Stephanie Roessler and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. TEAD Inhibitors Sensitize KRASPharmaceuticals (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Stefanie SchullerInstitute of Pathology, University Medicine Greifswald, 17475 Greifswald, Germany.
Jan SiekerInstitute of Pathology, University Medicine Greifswald, 17475 Greifswald, Germany.
Philip RiemenschneiderInstitute of Pathology, University Medicine Greifswald, 17475 Greifswald, Germany.
Bianca KöhlerInstitute of Pathology, University Medicine Greifswald, 17475 Greifswald, Germany.
Elisabeth DruckerInstitute of Pathology, University Medicine Greifswald, 17475 Greifswald, Germany.
Sofia M E WeilerInstitute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Daniel DauchDepartment of Internal Medicine VIII, University Hospital Tuebingen, 72076 Tuebingen, Germany.
Carsten StichtCore Facility Platform Mannheim (CFPM), NGS Core Facility, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Benjamin GoeppertInstitute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Stephanie RoesslerInstitute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-5333-5942
Silvia RibbackInstitute of Pathology, University Medicine Greifswald, 17475 Greifswald, Germany.
Kai BreuhahnInstitute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Falko FendInstitute of Pathology, University Hospital Tuebingen, 72076 Tuebingen, Germany.
Frank DombrowskiInstitute of Pathology, University Medicine Greifswald, 17475 Greifswald, Germany.
Kerstin SingerInstitute of Pathology, University Medicine Greifswald, 17475 Greifswald, Germany.
Stephan SingerInstitute of Pathology, University Medicine Greifswald, 17475 Greifswald, Germany.
Universitätsmedizin Greifswald · DEHeidelberg University · DEGerman Cancer Research Center · DEUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The major tumor suppressor P53 (

Indexed as

chromatin remodelinggene repressionHCCP53 network

Identifiers

PMID35053620
PMCPMC8773711
OpenAlexW4206259208

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.