Evidence map›Paper›PMID 35054089›Full record

ArticleJournal of clinical medicine2022

Rethinking the Body in the Brain after Spinal Cord Injury.

Erik Leemhuis, Valentina Giuffrida, Maria Luisa De Martino, Giuseppe Forte, Anna Pecchinenda, Luigi De Gennaro, Anna Maria Giannini, Mariella Pazzaglia

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Spinal Cord Injury and Loss of Cortical Inhibition.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Erik LeemhuisDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.ORCID 0000-0002-1430-4502
Valentina GiuffridaDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.ORCID 0000-0001-9109-0934
Maria Luisa De MartinoDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.
Giuseppe ForteDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.ORCID 0000-0002-5223-041X
Anna PecchinendaDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.ORCID 0000-0001-9139-5295
Luigi De GennaroDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.ORCID 0000-0003-3613-6631
Anna Maria GianniniDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.ORCID 0000-0002-0614-4457
Mariella PazzagliaDepartment of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy.ORCID 0000-0002-9196-7078
Fondazione Santa Lucia · ITSapienza University of Rome · IT

Funding

Ministry of Health RF-2018-12365682.
6 · The paper itself

Abstract

Spinal cord injuries (SCI) are disruptive neurological events that severly affect the body leading to the interruption of sensorimotor and autonomic pathways. Recent research highlighted SCI-related alterations extend beyond than the expected network, involving most of the central nervous system and goes far beyond primary sensorimotor cortices. The present perspective offers an alternative, useful way to interpret conflicting findings by focusing on the deafferented and deefferented body as the central object of interest. After an introduction to the main processes involved in reorganization according to SCI, we will focus separately on the body regions of the head, upper limbs, and lower limbs in complete, incomplete, and deafferent SCI participants. On one hand, the imprinting of the body's spatial organization is entrenched in the brain such that its representation likely lasts for the entire lifetime of patients, independent of the severity of the SCI. However, neural activity is extremely adaptable, even over short time scales, and is modulated by changing conditions or different compensative strategies. Therefore, a better understanding of both aspects is an invaluable clinical resource for rehabilitation and the successful use of modern robotic technologies.

Indexed as

body representationcentral nervous systemdeafferentationdisembodiedface representationlimb representationneural plasticityneuropathic painphantom limbrehabilitationsomatotopyspinal cord injury

Identifiers

PMID35054089
PMCPMC8780443
OpenAlexW4206815745

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.