Evidence map›Paper›PMID 35054831›Full record

ReviewInternational journal of molecular sciences2022

Biological Role, Mechanism of Action and the Importance of Interleukins in Kidney Diseases.

Paulina Mertowska, Sebastian Mertowski, Iwona Smarz-Widelska, Ewelina Grywalska

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
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  15. Article
  16. Interleukins: pathophysiological role in acute pancreatitis.Archives of medical science : AMS · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Paulina MertowskaDepartment of Experimental Immunology, Medical University of Lublin, 4A Chodzki Street, 20-093 Lublin, Poland.ORCID 0000-0001-9530-6659
Sebastian MertowskiDepartment of Experimental Immunology, Medical University of Lublin, 4A Chodzki Street, 20-093 Lublin, Poland.ORCID 0000-0002-7121-1396
Iwona Smarz-WidelskaDepartment of Nephrology, Cardinal Stefan Wyszynski Provincial Hospital in Lublin, Al. Kraśnicka Street, 20-718 Lublin, Poland.
Ewelina GrywalskaDepartment of Experimental Immunology, Medical University of Lublin, 4A Chodzki Street, 20-093 Lublin, Poland.ORCID 0000-0002-0451-4741
Medical University of Lublin · PL

Funding

Medical University of Lublin DS460National Science Center UMO-2016/23/B/NZ6/02844
6 · The paper itself

Abstract

Each year, the number of patients who are diagnosed with kidney disease too late is increasing, which leads to permanent renal failure. This growing problem affects people of every age, sex and origin, and its full etiopathogenesis is not fully understood, although the involvement of genetic susceptibility, infections, immune disorders or high blood pressure is suggested. Difficulties in making a correct and quick diagnosis are caused by the lack of research on early molecular markers, as well as educational and preventive activities among the public, which leads to the late detection of kidney diseases. An important role in the homeostasis and disease progression, including kidney diseases, is attributed to interleukins, which perform several biological functions and interact with other cells and tissues of the body. The aim of this article was to systematize the knowledge about the biological functions performed by interleukins in humans and their involvement in kidney diseases development. In our work, we took into account the role of interleukins in acute and chronic kidney disease and kidney transplantation.

Indexed as

BiomarkersDisease ProgressionEarly DiagnosisGene Expression RegulationHumansInterleukinsKidney DiseasesBiomarkersInterleukinsacute kidney diseasechronic kidney diseasecytokinekidney transplantation

Identifiers

PMID35054831
PMCPMC8775480
OpenAlexW4206690407

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.