Evidence map›Paper›PMID 35056546›Full record

ArticleMicroorganisms2022

Transcriptional Shift and Metabolic Adaptations during

Marlene Jara, Michael Barrett, Ilse Maes, Clement Regnault, Hideo Imamura, Malgorzata Anna Domagalska, Jean-Claude Dujardin

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Leishmaniasis.Nature reviews. Disease primers · 2025
    Review
  5. Article
  6. Frontiers in immunology · 2024
    Article
  7. Review
  8. Frontiers in immunology · 2023
    Article
  9. Article
  10. Unveiling drug-tolerant and persister-like cells inFrontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Marlene JaraMolecular Parasitology Unit, Institute of Tropical Medicine Antwerp, 2000 Antwerp, Belgium.ORCID 0000-0002-9739-3589
Michael BarrettWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.
Ilse MaesMolecular Parasitology Unit, Institute of Tropical Medicine Antwerp, 2000 Antwerp, Belgium.
Clement RegnaultWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.
Hideo ImamuraCentre for Medical Genetics, Universitair Ziekenhuis Brussel, 1090 Brussels, Belgium.ORCID 0000-0002-3282-1319
Malgorzata Anna DomagalskaMolecular Parasitology Unit, Institute of Tropical Medicine Antwerp, 2000 Antwerp, Belgium.
Jean-Claude DujardinMolecular Parasitology Unit, Institute of Tropical Medicine Antwerp, 2000 Antwerp, Belgium.ORCID 0000-0002-9217-5240
Instituut voor Tropische Geneeskunde · BEWellcome Centre for Molecular Parasitology · GBUniversitair Ziekenhuis Brussel · BEUniversity of Antwerp · BE

Funding

Wellcome Trust
6 · The paper itself

Abstract

Microorganisms can adopt a quiescent physiological condition which acts as a survival strategy under unfavorable conditions. Quiescent cells are characterized by slow or non-proliferation and a deep downregulation of processes related to biosynthesis. Although quiescence has been described mostly in bacteria, this survival skill is widespread, including in eukaryotic microorganisms. In

Indexed as

drug pressureLeishmaniaquiescence

Identifiers

PMID35056546
PMCPMC8781126
OpenAlexW4225822687

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.