Evidence map›Paper›PMID 35067150›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2022

Rational design and synthesis of 2-(1

Daseul Im, Joonhong Jun, Jihyun Baek, Haejin Kim, Dahyun Kang, Hyunah Bae, Hyunwook Cho, Jung-Mi Hah

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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  3. Review
  4. Unveiling Indazole: Novel Synthetic Pathways and Biological Potentials.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025
    Review
  5. Article
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  7. Review
  8. Binding Studies and Lead Generation of Pteridin-7(8International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Daseul ImDepartment of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.
Joonhong JunDepartment of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.
Jihyun BaekDepartment of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.
Haejin KimDepartment of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.
Dahyun KangDepartment of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.
Hyunah BaeDepartment of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.
Hyunwook ChoDepartment of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.
Jung-Mi HahDepartment of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea.
Hanyang University · KRAnyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fms-like tyrosine kinase 3 (FLT3) has been verified as a therapeutic target for acute myeloid leukaemia (AML). In this study, we report a series of 2-(1

Indexed as

Drug DesignBenzimidazolesCrystallography, X-RayDose-Response Relationship, Drugfms-Like Tyrosine Kinase 3HumansModels, MolecularMolecular StructureMutationProtein Kinase InhibitorsStructure-Activity RelationshipBenzimidazolesFLT3 protein, humanfms-Like Tyrosine Kinase 3Protein Kinase InhibitorsBenzimidazoleFLT3FLT3-D835YFLT3-ITDIndazole

Identifiers

PMID35067150
PMCPMC8788362
OpenAlexW4207047892

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.