Evidence map›Paper›PMID 35072010›Full record

ArticleiScience2022

Ultra-high-throughput Ca

Delia I Fernández, Isabella Provenzale, Hilaire Y F Cheung, Jan van Groningen, Bibian M E Tullemans, Alicia Veninga, Joanne L Dunster, Saman Honarnejad, Helma van den Hurk, Marijke J E Kuijpers and 1 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Suppressed ORAI1-STIM1-dependent CaThe Journal of biological chemistry · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Delia I FernándezDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
Isabella ProvenzaleDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
Hilaire Y F CheungDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
Jan van GroningenPivot Park Screening Centre, 5349 AB Oss, the Netherlands.
Bibian M E TullemansDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
Alicia VeningaDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
Joanne L DunsterInstitute for Cardiovascular and Metabolic Research, University of Reading, RG6 6AX Reading, UK.
Saman HonarnejadPivot Park Screening Centre, 5349 AB Oss, the Netherlands.
Helma van den HurkPivot Park Screening Centre, 5349 AB Oss, the Netherlands.
Marijke J E KuijpersDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
Johan W M HeemskerkDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6229 ER Maastricht, The Netherlands.
Maastricht University · NLMaastricht University Medical Centre · NLUniversidade de Santiago de Compostela · ESUniversity of Reading · GB

Funding

British Heart Foundation RG/15/2/31224British Heart Foundation RG/20/7/34866
6 · The paper itself

Abstract

Antiplatelet drugs targeting G-protein-coupled receptors (GPCRs), used for the secondary prevention of arterial thrombosis, coincide with an increased bleeding risk. Targeting ITAM-linked receptors, such as the collagen receptor glycoprotein VI (GPVI), is expected to provide a better antithrombotic-hemostatic profile. Here, we developed and characterized an ultra-high-throughput (UHT) method based on intracellular [Ca

Indexed as

Cell biologyFunctional aspects of cell biologyMethodology in biological sciences

Identifiers

PMID35072010
PMCPMC8762394
OpenAlexW4206180879

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.