Evidence map›Paper›PMID 35073064›Full record

ArticleBiochemistry2022

Conditional Alternative Protein Splicing Promoted by Inteins from

Vaishnavi R Yalala, Abigeal K Lynch, Kenneth V Mills

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vaishnavi R YalalaDepartment of Chemistry, College of the Holy Cross, 1 College Street, Worcester, Massachusetts 01610, United States.
Abigeal K LynchDepartment of Chemistry, College of the Holy Cross, 1 College Street, Worcester, Massachusetts 01610, United States.
Kenneth V MillsDepartment of Chemistry, College of the Holy Cross, 1 College Street, Worcester, Massachusetts 01610, United States.ORCID 0000-0001-6052-308X
College of the Holy Cross · US

Funding

The Regulation of Inteins: Adaptations in Extremophiles and Targets for Drug DiscoveryR15GM132817 · NIGMS · COLLEGE OF THE HOLY CROSS · PI MILLS, KENNETH V · 2019 to 2024
$723k
Acquisition of an Orbitrap MSS10OD010645 · OD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI EYLES, STEPHEN J. · 2013 to 2013
$600k
NIGMS NIH HHS R15 GM132817NIH HHS S10 OD010645
6 · The paper itself

Abstract

Protein splicing is a post-translational process by which an intervening protein, or an intein, catalyzes its own excision from flanking polypeptides, or exteins, coupled to extein ligation. Four inteins interrupt the MCM helicase of the halophile

Indexed as

InteinsProtein SplicingArchaeal ProteinsEscherichia coliExteinsHalobacteriaceaeMinichromosome Maintenance ProteinsPeptidesProtein PrecursorsArchaeal ProteinsMinichromosome Maintenance ProteinsPeptidesProtein Precursors

Identifiers

PMID35073064
PMCPMC8847336
OpenAlexW4207021023

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.