Evidence map›Paper›PMID 35073751›Full record

ArticlemBio2022

Mitochondria and Viral Infection: Advances and Emerging Battlefronts.

Mahsa Sorouri, Tyron Chang, Dustin C Hancks

Abstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mahsa Sorouri *Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Tyron Chang *Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Dustin C HancksDepartment of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-2720-2545

Funding

INTEGRATIVE IMMUNOLOGY TRAINING PROGRAMT32AI005284 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Nan Yan · 2003 to 2026
$7.4M
Evolution-guided Studies of Mitochondrial FunctionsR35GM142689 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI HANCKS, DUSTIN · 2021 to 2025
$2.0M
Evolution-guided Studies of Host-virus InterfacesR00GM119126 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI HANCKS, DUSTIN · 2018 to 2020
$747k
NIAID NIH HHS T32 AI005284NIGMS NIH HHS R00 GM119126NIGMS NIH HHS R35 GM142689
6 · The paper itself

Abstract

Mitochondria are dynamic organelles vital for energy production with now appreciated roles in immune defense. During microbial infection, mitochondria serve as signaling hubs to induce immune responses to counteract invading pathogens like viruses. Mitochondrial functions are central to a variety of antiviral responses including apoptosis and type I interferon signaling (IFN-I). While apoptosis and IFN-I mediated by

Indexed as

Interferon Type IVirus DiseasesAdaptor Proteins, Signal TransducingAntiviral AgentsHumansImmunity, InnateMitochondriaSignal TransductionAdaptor Proteins, Signal TransducingAntiviral AgentsInterferon Type IapoptosisC15orf48DAMPinterferonMAVSmicropeptidesmimicsMISTRmitochondriamitochondrial dynamicsmtDNAmtdsRNAmtROSNDUFA4OXPHOSpyroptosissupercomplexesTCA cyclevirologsvirus

Identifiers

PMID35073751
PMCPMC8787485

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.