Evidence map›Paper›PMID 35080048›Full record

ReviewJournal of gastroenterology and hepatology2022

Malaysian Society of Gastroenterology and Hepatology consensus statement on metabolic dysfunction-associated fatty liver disease.

Wah-Kheong Chan, Soek-Siam Tan, Siew-Pheng Chan, Yeong-Yeh Lee, Hoi-Poh Tee, Sanjiv Mahadeva, Khean-Lee Goh, Anis Safura Ramli, Feisul Mustapha, Nik Ritza Kosai and 1 more

Open access · greenAbstract readReviewConsensus Statement
In one paragraph

Review in Journal of gastroenterology and hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. [Analysis of a study for the global trend burden of MAFLD-associated cirrhosis based on the 2024 update of the Global Burden of Disease Database].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. MAFLD: from a disease framework to patient care.Hepatology international · 2024
    Article
  16. Liver dysfunction in adults with COVID-19 infection: A longitudinal study with transient elastography evaluation.JGH open : an open access journal of gastroenterology and hepatology · 2024
    Article
  17. Metabolic associated fatty liver disease (MAFLD): assessing the knowledge and practice of primary care doctors in Seremban District, Negeri Sembilan.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2024
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Wah-Kheong ChanGastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-9105-5837
Soek-Siam TanDepartment of Hepatology, Selayang Hospital, Batu Caves, Selangor, Malaysia.
Siew-Pheng ChanSubang Jaya Medical Centre, Subang Jaya, Selangor, Malaysia.
Yeong-Yeh LeeSchool of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia.ORCID https://orcid.org/0000-0002-6486-7717
Hoi-Poh TeeKPJ Pahang Specialist Centre, Kuantan, Pahang, Malaysia.
Sanjiv MahadevaGastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0001-5824-0590
Khean-Lee GohGastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-9965-1561
Anis Safura RamliDepartment of Primary Care Medicine, Faculty of Medicine, Universiti Teknologi MARA, Selayang Campus, Batu Caves, Selangor, Malaysia.
Feisul MustaphaDisease Control Division, Ministry of Health, Malaysia, Putrajaya, Malaysia.
Nik Ritza KosaiUpper Gastrointestinal, Metabolic and Bariatric Surgery Unit, Department of Surgery, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Raja Affendi Raja AliGastroenterology Unit, Department of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
University of Malaya · MYHospital Selayang · MYUniversity Kebangsaan Malaysia Medical Centre · MYHospital Universiti Sains Malaysia · MYMinistry of Health · MYSubang Jaya Medical Centre · MYUniversiti Malaysia Pahang Al-Sultan Abdullah · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Malaysian Society of Gastroenterology and Hepatology saw the need for a consensus statement on metabolic dysfunction-associated fatty liver disease (MAFLD). The consensus panel consisted of experts in the field of gastroenterology/hepatology, endocrinology, bariatric surgery, family medicine, and public health. A modified Delphi process was used to prepare the consensus statements. The panel recognized the high and increasing prevalence of the disease and the consequent anticipated increase in liver-related complications and mortality. Cardiovascular disease is the leading cause of mortality in MAFLD patients; therefore, cardiovascular disease risk assessment and management is important. A simple and clear liver assessment and referral pathway was agreed upon, so that patients with more severe MAFLD can be linked to gastroenterology/hepatology care, while patients with less severe MAFLD can remain in primary care or endocrinology, where they are best managed. Lifestyle intervention is the cornerstone in the management of MAFLD. The panel provided a consensus on the use of statin, angiotensin-converting enzyme inhibitor or angiotensin receptor blocker, sodium-glucose cotransporter-2 inhibitor, glucagon-like peptide-1 agonist, pioglitazone, vitamin E, and metformin, as well as recommendations on bariatric surgery, screening for gastroesophageal varices and hepatocellular carcinoma, and liver transplantation in MAFLD patients. Increasing the awareness and knowledge of the various stakeholders on MAFLD and incorporating MAFLD into existing noncommunicable disease-related programs and activities are important steps to tackle the disease. These consensus statements will serve as a guide on MAFLD for clinicians and other stakeholders.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2GastroenterologyLiver NeoplasmsNon-alcoholic Fatty Liver DiseaseSodium-Glucose Transporter 2 InhibitorsHumansSodium-Glucose Transporter 2 InhibitorsconsensusMAFLDMalaysiaMalaysian Society of Gastroenterology and Hepatologymetabolic dysfunction-associated fatty liver diseaseMSGHmulti-disciplinaryNAFLDnon-alcoholic fatty liver disease

Identifiers

PMID35080048
PMCPMC9303255
OpenAlexW4210460200

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.