ArticlePlant physiology2022
Analysis of exocyst function in endodermis reveals its widespread contribution and specificity of action.
Article in Plant physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Exocyst subunits EXO70B1 and B2 contribute to stomatal dynamics and cell wall modifications.Frontiers in plant science · 2025Article
- Synergism of vesicle trafficking and cytoskeleton during regulation of plant growth and development: A mechanistic outlook.Heliyon · 2023Review
- Mechanosensation in leaf veins.Science advances · 2023Article
- Exo84c interacts with VAP27 to regulate exocytotic compartment degradation and stigma senescence.Nature communications · 2023Article
- Specificity models in MAPK cascade signaling.FEBS open bio · 2023Review
- Directed growth and fusion of membrane-wall microdomains requires CASP-mediated inhibition and displacement of secretory foci.Nature communications · 2023Article
- The EXO70 inhibitor Endosidin2 alters plasma membrane protein composition in Arabidopsis roots.Frontiers in plant science · 2023Article
- Rab GTPases, tethers, and SNAREs work together to regulateFrontiers in plant science · 2023Review
- Exocyst function and specificity during Casparian strip formation-insights via a gene-edited endodermis.Plant physiology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The exocyst is the main plasma membrane vesicle-tethering complex in eukaryotes and is composed of eight different subunits. Yet, in plant genomes, many subunits display multiple copies, thought to reflect evolution of complex subtypes with divergent functions. In Arabidopsis thaliana root endodermal cells, the isoform EXO70A1 is required for positioning of CASP1 at the Casparian Strip Domain, but not for its non-targeted secretion to the plasma membrane. Here, we show that exo84b resembles exo70a1 mutants regarding CASP1 mistargeting and secretion of apoplastic proteins, but exo84b additionally affects secretion of other integral plasma membrane proteins. Moreover, conditional, cell-type-specific gene editing of the single-copy core component SEC6 allows visualization of secretion defects in plant cells with a complete lack of exocyst complex function. Our approach opens avenues for deciphering the complexity/diversity of exocyst functions in plant cells and enables analysis of central trafficking components with lethal phenotypes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.