Evidence map›Paper›PMID 35102145›Full record

ArticleBlood cancer journal2022

Efficacy of CDK9 inhibition in therapy of post-myeloproliferative neoplasm (MPN) secondary (s) AML cells.

Warren Fiskus, Taghi Manshouri, Christine Birdwell, Christopher P Mill, Lucia Masarova, Prithviraj Bose, Tapan M Kadia, Naval Daver, Courtney D DiNardo, Gautam Borthakur and 3 more

Abstract readLetter
In one paragraph

Article in Blood cancer journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Warren FiskusThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-7343-6214
Taghi ManshouriThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Christine BirdwellThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Christopher P MillThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Lucia MasarovaThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Prithviraj BoseThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-4343-5712
Tapan M KadiaThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-9892-9832
Naval DaverThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0001-7103-373X
Courtney D DiNardoThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0001-9003-0390
Gautam BorthakurThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0001-7679-6453
Joseph D KhouryThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0003-2621-3584
Srdan VerstovsekThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-6912-8569
Kapil N BhallaThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA. kbhalla@mdanderson.org.ORCID 0000-0001-5209-5126

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
Targeting dysregulated transcriptome as therapy for post-myeloproliferative neoplasm (MPN) sAMLR01CA233457 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BHALLA, KAPIL, VERSTOVSEK, SRDAN · 2020 to 2024
$2.3M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA233457
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntineoplastic AgentsCell Line, TumorCyclin-Dependent Kinase 9HumansLeukemia, Myeloid, AcuteMiceMyeloproliferative DisordersProtein Kinase InhibitorsTumor Cells, CulturedAntineoplastic AgentsCDK9 protein, humanCyclin-Dependent Kinase 9Protein Kinase Inhibitors

Identifiers

PMID35102145
PMCPMC8803998

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.