ArticleBMC plant biology2022
SPL9 mediates freezing tolerance by directly regulating the expression of CBF2 in Arabidopsis thaliana.
Article in BMC plant biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 57 citations in OpenAlex.
- Distinct processes contributing to post-submergence recovery determine leaf age-specific flood resilience in Arabidopsis.Plant physiology · 2026Article
- Splicing Factor SR45 Enhances Cold Tolerance in Cassava by Recruiting Nu4A Complex and Transcription Factors to Activate WRKY30.Plant, cell & environment · 2026Article
- miR156-StSPL9 regulating the biosynthesis of flavonoids and secondary metabolites in potato tubers.BMC plant biology · 2026Article
- SBP-Box Transcription Factor JcSPL9 Regulates Both Seed Yield and Oil Content in the Biofuel Plant Jatropha curcas.Plant biotechnology journal · 2026Article
- Genome-Wide Identification and Expression Profiling of the SPL Gene Family inPlants (Basel, Switzerland) · 2026Article
- Cu-miRNA-mediated redox homeostasis explains the differences in cold tolerance between AAA and ABB banana varieties.Journal of advanced research · 2026Article
- Multifaceted Roles of SPL9 in Plant Growth, Development, and Stress Responses: A Review.Plants (Basel, Switzerland) · 2026Review
- Evolutionary History, Transcriptome Expression Profiles, and Abiotic Stress Responses of theInternational journal of molecular sciences · 2026Article
- SQUAMOSA-Promoter Binding Protein Like 10/14 (OsSPL10/14) Regulate Salt Tolerance by Modulating Reactive Oxygen Species Homeostasis in Rice (Oryza Sativa L.).Rice (New York, N.Y.) · 2025Article
- Non-coding RNAs in plant stress responses: molecular insights and agricultural applications.Plant biotechnology journal · 2025Review
- Identification and characterization of long non-coding RNA (lncRNA) in wild and semi-wild cucumbers.BMC plant biology · 2025Article
- Identification and Characterization of SQUAMOSA Promoter Binding Protein-like Transcription Factor Family Members inPlants (Basel, Switzerland) · 2025Article
- Phylogenetic and Expression Analysis of SBP-Box Gene Family to Enhance Environmental Resilience and Productivity inPlants (Basel, Switzerland) · 2025Article
- Unraveling the signaling pathways of plant cold stress: current insights and future directions.Frontiers in plant science · 2025Review
- Unraveling the multifaceted roles of SPL transcription factors in leaf development.Frontiers in plant science · 2025Review
- TheFrontiers in plant science · 2025Article
- Genome-Wide Identification and Expression Profiling of thePlants (Basel, Switzerland) · 2024Article
- Molecular Mechanisms Underlying Freezing Tolerance in Plants: Implications for Cryopreservation.International journal of molecular sciences · 2024Review
- Identification and Functional Studies on the Role ofInternational journal of molecular sciences · 2024Article
- Genome-wide identification and expression analysis of the SPL transcription factor family and its response to abiotic stress in Pisum sativum L.BMC genomics · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundFreezing stress inhibits plant development and causes significant damage to plants. Plants therefore have evolved a large amount of sophisticated mechanisms to counteract freezing stress by adjusting their growth and development correspondingly. Plant ontogenetic defense against drought, high salt, and heat stresses, has been extensively studied. However, whether the freezing tolerance is associated with ontogenetic development and how the freezing signals are delivered remain unclear.
resultsIn this study, we found that the freezing tolerance was increased with plant age at the vegetative stage. The expressions of microRNA156 (miR156) and SQUAMOSA PROMOTER BINDING PROTEIN-LIKE 9 (SPL9), playing roles in regulation of ontogenetic development, were induced by cold stress. Overexpression of SPL9 (rSPL9) promoted the expression of C-REPEAT BINDING FACTOR 2 (CBF2) and hereafter enhanced the freezing tolerance. Genetic analysis indicated that the effect of rSPL9 on freezing tolerance is partially restored by cbf2 mutant. Further analysis confirmed that SPL9 directly binds to the promoter of CBF2 to activate the expression of CBF2, and thereafter increased the freezing tolerance.
conclusionsTherefore, our study uncovers a new role of SPL9 in fine-tuning CBF2 expression and thus mediating freezing tolerance in plants, and implies a role of miR156-SPL pathway in balancing the vegetative development and freezing response in Arabidopsis.
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