ArticleFrontiers in cell and developmental biology2021
Transcriptomic and Metabolomic Analyses Reveal Inhibition of Hepatic Adipogenesis and Fat Catabolism in Yak for Adaptation to Forage Shortage During Cold Season.
Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 16 citations in OpenAlex.
- Comparative Quantitative Profiling of Protein Lactylation Reveals a Dynamic Tissues-Specific Network Associated with Metabolic Specialization in Yaks.Animals : an open access journal from MDPI · 2026Article
- Effects of Concentrates with Different Energy and Protein Levels on Growth Performance, Blood Metabolism, and Rumen Microbiota of Housed Pregnant Yaks During the Warm Season.Microorganisms · 2026Article
- The price of survival: comparative adaptation to high altitudes between yaks and cattle.Animal microbiome · 2026Article
- Activation of the RAS/PPARα pathway reduces backfat deposition of Gayal (Bos frontalis).BMC genomics · 2026Article
- Effects of Different Feeding Modes on Growth Performance, Blood Biochemistry, and Metabolism of Yushu Yaks During the Cold Season.Animals : an open access journal from MDPI · 2026Article
- Metagenomic and metabolomic analyses of rumen fiber digestion in Mongolian cattle fed fresh grass versus hay.Microbiology spectrum · 2026Article
- Dietary Guanidinoacetic Acid Supplementation Improves Growth Performance of Plateau Yaks Through Plasma Metabolome Modulation.Biology · 2025Article
- Bioinformatics Analysis of Candidate Genes Related to Fat Deposition in Yaks at Different Energy Levels.Current issues in molecular biology · 2025Article
- Quantitative Proteomics Revealed the Molecular Regulatory Network of Lysine and the Effects of Lysine Supplementation on Sunit Skeletal Muscle Satellite Cells.Animals : an open access journal from MDPI · 2025Article
- Transcriptomic Analysis of Skin Tissue Reveals Molecular Mechanisms of Thermal Adaptation in Cold-Exposed Lambs.Animals : an open access journal from MDPI · 2025Article
- Transcriptomics and metabolomics insights into the seasonal dynamics of meat quality in yak on the Qinghai-Tibetan Plateau.BMC genomics · 2024Article
- Liver Transcriptome Analysis Reveals the Mechanisms of Metabolic Adaptation of Xizang Sheep to Seasonal Changes.Metabolites · 2024Article
- Quantitative Proteomic Analysis of Tibetan Pig Livers at Different Altitudes.Molecules (Basel, Switzerland) · 2023Article
- Article
- Editorial: RNA-Mediated Epigenetic and Transcriptional Regulation.Frontiers in genetics · 2022Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animals have adapted behavioral and physiological strategies to conserve energy during periods of adverse conditions. Hepatic glucose is one such adaptation used by grazing animals. While large vertebrates have been shown to have feed utilization and deposition of nutrients-fluctuations in metabolic rate-little is known about the regulating mechanism that controls hepatic metabolism in yaks under grazing conditions in the cold season. Hence, the objective of this research was to integrate transcriptomic and metabolomic data to better understand how the hepatic responds to chronic nutrient stress. Our analyses indicated that the blood parameters related to energy metabolism (glucose, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, lipoprotein lipase, insulin, and insulin-like growth factor 1) were significantly (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.