ArticleAutism research : official journal of the International Society for Autism Research2022
Association between atopic diseases and neurodevelopmental disabilities in a longitudinal birth cohort.
Article in Autism research : official journal of the International Society for Autism Research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Bidirectional association between atopic dermatitis and attention deficit hyperactivity disorder: a systematic review and meta-analysis.Annals of medicine · 2025Pooled it
- Examining the association between autism spectrum disorder and atopic eczema: meta-analysis of current evidence.Pediatric research · 2025Pooled it
- Pooled it
- Atopic dermatitis and attention-deficit/hyperactivity disorder comorbidity in children and adolescents: Epidemiology, mechanisms, and clinical management.Pediatric investigation · 2026Review
- Article
- Individual and Combined Associations of Maternal Fever, Placental Inflammation, and Prematurity With Autism and ADHD.Journal of autism and developmental disorders · 2026Article
- Mindful approaches: Association between atopic dermatitis and autism spectrum disorder and use of visual storyboards.Dermatology online journal · 2026Article
- Allergic rhinitis and behaviour problems in urban children aged 6 to 12 years and the mediating role of sleep disturbance.Annals of medicine · 2025Article
- Atopic dermatitis and executive function across early and middle childhood - A longitudinal cohort study of children in the United Kingdom.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025Article
- Risk behaviours and non-atopic comorbidities of adolescents with asthma.The World Allergy Organization journal · 2025Article
- Associations and Related Mechanisms of Attention-Deficit Hyperactivity Disorder and Allergic Rhinitis in Children.Psychiatry and clinical psychopharmacology · 2025Review
- Atopic Dermatitis and Autism Spectrum Disorders: Common Role of Environmental and Clinical Co-Factors in the Onset and Severity of Their Clinical Course.International journal of molecular sciences · 2024Review
- Early childhood neurodevelopmental milestones in children with allergic diseases: the Japan Environment and Children's Study (JECS).Scientific reports · 2024Article
- Early Life Origins of Neurodevelopmental Disabilities in the Boston Birth Cohort: Research findings and future directions.Precision nutrition · 2024Article
- Association between type 2 inflammatory diseases and neurodevelopmental disorders in low-birth-weight children and adolescents.Frontiers in psychology · 2024Article
- RNA sequencing of blood from sex- and age-matched discordant siblings supports immune and transcriptional dysregulation in autism spectrum disorder.Scientific reports · 2023Article
- Link between the skin and autism spectrum disorder.Frontiers in psychiatry · 2023Article
- Atopic dermatitis and risk of major neuropsychiatric disorders in children: A population-based cohort study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2023Article
- Sex-specific associations among infant food and atopic sensitizations and infant neurodevelopment.Frontiers in pediatrics · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
Reports on the association between the prevalence of atopic diseases and neurodevelopmental disabilities (NDs) have been inconsistent in the literature. We investigated whether autism spectrum disorder (ASD), attention deficit-hyperactivity disorders (ADHD), and other NDs are more prevalent in children with asthma, atopic dermatitis (AD) and allergic rhinitis (AR) compared to those without specific atopic conditions. A total of 2580 children enrolled at birth were followed prospectively, of which 119 have ASD, 423 have ADHD, 765 have other NDs, and 1273 have no NDs. Atopic diseases and NDs were defined based on physician diagnoses in electronic medical records. Logistic regressions adjusting for maternal and child characteristics estimated the associations between NDs (i.e., ASD, ADHD, and other NDs) and asthma, AD and AR, respectively. Children with asthma, AD or AR had a greater likelihood of having ADHD or other NDs compared with children without specific atopic conditions. The association between ASD and asthma diminished after adjusting for maternal and child factors. Either mothers or children having atopic conditions and both mothers and children with atopic conditions were associated with a higher prevalence of ADHD in children, compared with neither mothers nor children having atopic conditions. Children diagnosed with multiple atopic diseases were more likely to have NDs compared with those without or with only one type of atopic disease. In conclusion, in this U.S. urban birth cohort, children with atopic diseases had a higher co-morbidity of NDs. The findings have implications for etiologic research that searches for common early life antecedents of NDs and atopic conditions. Findings from this study also should raise awareness among health care providers and parents about the possible co-occurrence of both NDs and atopic conditions, which calls for coordinated efforts to screen, prevent and manage NDs and atopic conditions.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.