ArticleNature communications2022
Characterising within-hospitalSARS-CoV-2 transmission events using epidemiological and viral genomic data across two pandemic waves.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Telemedicine to Support Heart Failure Patients during Social Distancing: A Systematic Review.Global heart · 2022Pooled it
- Differential Odds of COVID-19 Infection Associated With Household and Workplace Exposures in US Health Care Personnel.Journal of occupational and environmental medicine · 2026Article
- Risk of Infections Among Contacts of COVID-19 Cases in the Healthcare Setting: Experience of One University Hospital.Epidemiologia (Basel, Switzerland) · 2025Article
- Modelling the potential use of pre-exposure prophylaxis to reduce nosocomial SARS-CoV-2 transmission.PLoS computational biology · 2025Article
- The potential of genomic epidemiology: capitalizing on its practical use for impact in the healthcare setting.Frontiers in public health · 2025Article
- The Italian public health response during the pandemic emergency: from qualitative data to the "performance index" of care provided by Spoleto Hospital.Frontiers in public health · 2025Article
- Dynamic contagion potential framework for optimizing infection control in healthcare.Frontiers in public health · 2025Article
- Post-exposure testing at healthcare facilities with SARS-CoV-2 transmission: A rapid review.Journal of public health in Africa · 2025Review
- Consistent FFP2-masking as part of reducing viral respiratory infections on medical wards for allogeneic hematopoietic stem cell transplantation.Scientific reports · 2024Article
- Article
- COVID-19-related temporary disability in healthcare workers in Spain during the four first pandemic waves.Preventive medicine reports · 2024Article
- Impact of interventions to reduce nosocomial transmission of SARS-CoV-2 in English NHS Trusts: a computational modelling study.BMC infectious diseases · 2024Article
- Article
- Outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 in a Rural Community Hospital during Omicron Predominance.Microorganisms · 2024Article
- Assessing respiratory epidemic potential in French hospitals through collection of close contact data (April-June 2020).Scientific reports · 2024Article
- The effectiveness and efficiency of asymptomatic SARS-CoV-2 testing strategies for patient and healthcare workers within acute NHS hospitals during an omicron-like period.BMC infectious diseases · 2024Article
- Sorting out assortativity: When can we assess the contributions of different population groups to epidemic transmission?PloS one · 2024Article
- Evaluating pooled testing for asymptomatic screening of healthcare workers in hospitals.BMC infectious diseases · 2023Article
- A novel opportunity to improve heart failure care: focusing on subcutaneous furosemide.Heart failure reviews · 2023Review
- Article
Corrections and comments
- Erratum issued
Authors and funding
28 authors.
Funding
Abstract
Hospital outbreaks of COVID19 result in considerable mortality and disruption to healthcare services and yet little is known about transmission within this setting. We characterise within hospital transmission by combining viral genomic and epidemiological data using Bayesian modelling amongst 2181 patients and healthcare workers from a large UK NHS Trust. Transmission events were compared between Wave 1 (1st March to 25th J'uly 2020) and Wave 2 (30th November 2020 to 24th January 2021). We show that staff-to-staff transmissions reduced from 31.6% to 12.9% of all infections. Patient-to-patient transmissions increased from 27.1% to 52.1%. 40%-50% of hospital-onset patient cases resulted in onward transmission compared to 4% of community-acquired cases. Control measures introduced during the pandemic likely reduced transmissions between healthcare workers but were insufficient to prevent increasing numbers of patient-to-patient transmissions. As hospital-acquired cases drive most onward transmission, earlier identification of nosocomial cases will be required to break hospital transmission chains.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.