Evidence map›Paper›PMID 35122246›Full record

ReviewInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2022

Nutritional interventions to ameliorate the effect of endocrine disruptors on human reproductive health: A semi-structured review from FIGO.

Gillian A Corbett, Sadhbh Lee, Tracey J Woodruff, Mark Hanson, Moshe Hod, Anne Marie Charlesworth, Linda Giudice, Jeanne Conry, Fionnuala M McAuliffe, International Federation of Gynecology and Obstetrics (FIGO) Committee on Impact of Pregnancy on Long-term Health and the FIGO Committee on Climate Change and Toxic Environmental Exposures

Registry-linked trialAbstract readReview
In one paragraph

Review in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07560579 (Weight Loss and Endocrine Disrupting Chemicals), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07560579 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity

TypeinterventionalSponsorMillion Marker Wellness, Inc.Ran2025 to 2026Enrolled226ConditionsObesity &Amp, Amp, Amp, OverweightArmsEducational curriculum, Weight loss Application, Urinary EDC metabolite testing, Siphox clinic biomarker test, Weight loss reporting
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Observational
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. FIGO committee opinion: Environmental drivers of gynecologic and reproductive health.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  9. FIGO committee opinion: Environmental drivers of obstetric health and early childhood development.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Nutritional interventions to ameliorate the effect of endocrine disruptors on human reproductive health: A semi-structured review from FIGO.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gillian A CorbettUCD Perinatal Research Centre, UCD School of Medicine, University College Dublin, National Maternity Hospital, Dublin, Ireland.
Sadhbh LeeUCD Perinatal Research Centre, UCD School of Medicine, University College Dublin, National Maternity Hospital, Dublin, Ireland.
Tracey J WoodruffProgram on Reproductive Health and Environment, Department of Obstetrics and Gynecology, Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, California, USA.
Mark HansonInternational Federation of Gynaecology and Obstetrics (FIGO) Committee on Impact of Pregnancy on Long-term Health, Dublin.
Moshe HodInternational Federation of Gynaecology and Obstetrics (FIGO) Committee on Impact of Pregnancy on Long-term Health, Dublin.
Anne Marie CharlesworthProgram on Reproductive Health and Environment, Department of Obstetrics and Gynecology, Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, California, USA.
Linda GiudiceInternational Federation of Gynecology and Obstetrics (FIGO) Committee on Climate Change and Toxic Environmental Exposures.
Jeanne ConryEnvironmental Health and Leadership Foundation, USA.
Fionnuala M McAuliffeUCD Perinatal Research Centre, UCD School of Medicine, University College Dublin, National Maternity Hospital, Dublin, Ireland.
International Federation of Gynecology and Obstetrics (FIGO) Committee on Impact of Pregnancy on Long-term Health and the FIGO Committee on Climate Change and Toxic Environmental Exposures

Funding

UCSF Environmental Research and Translation for Health Center (EaRTH Center)P30ES030284 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Rashmi Joglekar · 2020 to 2026
$11.2M
JPB Foundation 1P30ES030284 - 01A1NIEHS NIH HHS P30 ES030284
6 · The paper itself

Abstract

backgroundEndocrine disrupting chemicals have harmful effects on reproductive, perinatal, and obstetric outcomes.

objectiveTo analyze the evidence on nutritional interventions to reduce the negative effects of endocrine disruptors on reproductive, perinatal, and obstetric outcomes. SEARCH STRATEGY: A search of MEDLINE (PubMed), Allied Health Literature (CINAHL), EMBASE, Web of Science, and the Cochrane Database was conducted from inception to May 2021. SELECTION CRITERIA: Experimental studies on human populations. DATA COLLECTION AND ANALYSIS: Data were collected from eligible studies. Risk of bias assessment was completed using the Cochrane risk of bias tool and the ROBINS-I Tool.

resultsDatabase searches yielded 15 362 articles. Removing 11 181 duplicates, 4181 articles underwent abstract screening, 26 articles were eligible for full manuscript review, and 16 met full inclusion criteria. Several interventions were found to be effective in reducing exposure to endocrine disruptors: avoidance of plastic containers, bottles, and packaging; avoidance of canned food/beverages; consumption of fresh and organic food; avoidance of fast/processed foods; and supplementation with vitamin C, iodine, and folic acid. There were some interventional studies examining therapies to improve clinical outcomes related to endocrine disruptors.

conclusionDietary alterations can reduce exposure to endocrine disruptors, with limited data on interventions to improve endocrine-disruptor-related clinical outcomes. This review provides useful instruction to women, their families, healthcare providers, and regulatory bodies.

Indexed as

Endocrine DisruptorsFemaleHumansPregnancyReproductive HealthVitaminsEndocrine DisruptorsVitaminsendocrine disruptorslifestyle interventionsnutritional interventionsperinatal morbidityreproductive outcomes

Identifiers

PMID35122246
PMCPMC9305939

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.