Evidence map›Paper›PMID 35124825›Full record

ReviewParasite immunology2022

Hookworm infections: Reappraising the evidence for a role of neutrophils in light of NETosis.

Rory Doolan, Tiffany Bouchery

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Parasite immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. NETosis in Parasitic Infections: A Puzzle That Remains Unsolved.International journal of molecular sciences · 2023
    Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rory DoolanSwiss Tropical and Public Health Institute, Department of Medical Parasitology & Infection Biology, HDDU-HIB laboratory, Allschwill, Switzerland.ORCID 0000-0001-9592-7607
Tiffany BoucherySwiss Tropical and Public Health Institute, Department of Medical Parasitology & Infection Biology, HDDU-HIB laboratory, Allschwill, Switzerland.ORCID 0000-0003-3743-7356
Swiss Tropical and Public Health Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Hookworm infection, neutrophils have long had the image of the villain, being recruited to the site of larval migration because of damage but participating themselves in tissue injury. With recent developments in neutrophil biology, there is an increasing body of evidence for the role of neutrophils as effector cells in hookworm immunity. In particular, their ability to release extracellular traps, or neutrophil extracellular traps (NETs), confer neutrophils a larvicidal activity. Here, we review recent evidence in this nascent field and discuss the avenue for future research on NETs/hookworm interactions.

Indexed as

Extracellular TrapsHookworm InfectionsAncylostomatoideaAnimalsNeutrophilshelminthhookwormsNETosisneutrophil extracellular trapsneutrophils

Identifiers

PMID35124825
PMCPMC9285577
OpenAlexW4210738225

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.