Evidence map›Paper›PMID 35130427›Full record

ArticleNeurospine2022

Sacral Nerves Reconstruction After Surgical Resection of a Large Sacral Chordoma Restores the Urinary and Sexual Function and the Anal Continence.

Luigi Valentino Berra, Daniele Armocida, Mauro Palmieri, Valerio Di Norcia, Luca D'Angelo, Massimo Mongardini, Massimo Vigliotta, Edoardo Maccari, Antonio Santoro

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurospine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Luigi Valentino BerraA.U.O. "Policlinico Umberto I", Neurosurgery Division, Sapienza University, Human Neurosciences Department, Roma, Italy.
Daniele ArmocidaA.U.O. "Policlinico Umberto I", Neurosurgery Division, Sapienza University, Human Neurosciences Department, Roma, Italy.
Mauro PalmieriA.U.O. "Policlinico Umberto I", Neurosurgery Division, Sapienza University, Human Neurosciences Department, Roma, Italy.
Valerio Di NorciaA.U.O. "Policlinico Umberto I", Neurosurgery Division, Sapienza University, Human Neurosciences Department, Roma, Italy.
Luca D'AngeloA.U.O. "Policlinico Umberto I", Neurosurgery Division, Sapienza University, Human Neurosciences Department, Roma, Italy.
Massimo MongardiniA.U.O. "Policlinico Umberto I", Dipartimento di Chirurgia Generale, Sapienza University, Roma, Italy.
Massimo VigliottaA.U.O. "Policlinico Umberto I", Neurosurgery Division, Sapienza University, Human Neurosciences Department, Roma, Italy.
Edoardo MaccariA.U.O. "Policlinico Umberto I", Neurosurgery Division, Sapienza University, Human Neurosciences Department, Roma, Italy.
Antonio SantoroA.U.O. "Policlinico Umberto I", Neurosurgery Division, Sapienza University, Human Neurosciences Department, Roma, Italy.
Policlinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveChordomas are slow-growing tumors, with a high tendency to local relapse. En bloc resection is related to the most favorable outcome in terms of survival but is frequently associated with permanent neurological deficits involving sphincters and sexual functions. In the present article, we describe an innovative technique of en bloc resection followed by reconstruction of the sacral nerves with nerve grafts.

methodsThe chordoma was excised through a posterior approach after dividing the proximal and distal sacral nerves using the established technique. After that, a microsurgical S2-S3-S4 nerve reconstruction was performed connecting the proximal and distal stumps with sural nerve grafts withdrawn from both lower limbs.

resultsImmediately after surgery, the patient experienced complete impairment of sexual function and sphincters with urinary and fecal incontinence. After 6 months, there was a progressive recovery of sexual function and sphincter control. One year after the operation, the patient achieved an adequate sexual life (erection and ejaculation) and complete control of the bladder and anal sphincter.

conclusionReconstruction of nerves sacrificed during sacral tumor removal has been shown to be effective in restoring sphincter and sexual function and is a promising technique that may significantly improve patients' quality of life.

Indexed as

ChordomaComplicationsFecal incontinenceNerve reconstruction

Identifiers

PMID35130427
PMCPMC8987555
OpenAlexW4210426902

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.