ArticleBMJ (Clinical research ed.)2022
Early phase clinical trials extension to guidelines for the content of statistical analysis plans.
Article in BMJ (Clinical research ed.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Expansion cohorts in phase 1 oncology trials: a systematic review of their design, implementation and outcomes.British journal of cancer · 2026Pooled it
- A systematic review of chiropractic care for fall prevention: rationale, state of the evidence, and recommendations for future research.BMC musculoskeletal disorders · 2022Pooled it
- Evaluating how clear the questions being investigated in randomised trials are: systematic review of estimands.BMJ (Clinical research ed.) · 2022Pooled it
- Defining estimands in anaesthesia clinical trials: a scoping review and framework.British journal of anaesthesia · 2026Article
- Aligning Estimands to Strengthen the Credibility of Network Meta-Analysis: Implications for Indirect Treatment Comparisons.Statistics in biopharmaceutical research · 2026Article
- CRT-Estimands Framework: consensus based extension of the ICH E9(R1) addendum for cluster randomised trials.BMJ (Clinical research ed.) · 2026Article
- International Consensus-Driven Recommendations for Patient-Reported Outcome Research Objectives in Early Phase Dose-Finding Oncology Trials: OPTIMISE-ROR.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026Article
- Clinical Trial Simulation: Planning With the OCTAVE Framework, Implementation and Validation Principles.Statistics in medicine · 2026Article
- Using Dose-Escalation and -Expansion Cohort Study as Pivotal Trial for Targeted Anticancer Drug Approval.JCO precision oncology · 2025Review
- SPIRIT 2025 explanation and elaboration: updated guideline for protocols of randomised trials.BMJ (Clinical research ed.) · 2025Article
- CONSORT 2025 explanation and elaboration: updated guideline for reporting randomised trials.BMJ (Clinical research ed.) · 2025Article
- Article
- SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocols.EClinicalMedicine · 2025Article
- CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trials.EClinicalMedicine · 2025Article
- Article
- A randomised controlled phase II trial to examine the feasibility of using hyper-oxygenated fatty acids (HOFA) to prevent facial pressure injuries from medical devices among adults admitted to intensive care-A research protocol.International wound journal · 2024Article
- Good Statistical Practice-development of tailored Good Clinical Practice training for statisticians.Trials · 2024Review
- Determining a risk-proportionate approach to the validation of statistical programming for clinical trials.Clinical trials (London, England) · 2024Review
- The estimands framework: a primer on the ICH E9(R1) addendum.BMJ (Clinical research ed.) · 2024Article
- Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance.BMJ (Clinical research ed.) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.