Evidence map›Paper›PMID 35132851›Full record

ArticleBiomacromolecules2022

Lipid Membrane Binding and Cell Protection Efficacy of Poly(1,2-butylene oxide)-

Nicholas J Van Zee, Amanda S Peroutka, Adelyn Crabtree, Marc A Hillmyer, Timothy P Lodge

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomacromolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Discovery of Kinetic Trapping of Poloxamers inside Liposomes via Thermal Treatment.Langmuir : the ACS journal of surfaces and colloids · 2023
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nicholas J Van ZeeORCID 0000-0003-1370-6443
Amanda S Peroutka
Adelyn Crabtree
Marc A HillmyerORCID 0000-0001-8255-3853
Timothy P LodgeORCID 0000-0001-5916-8834
University of Minnesota · US

Funding

Targeted membrane integrity in cardiac ischemia and reperfusionR01HL122323 · NHLBI · UNIVERSITY OF MINNESOTA · PI METZGER, JOSEPH MARK · 2015 to 2022
$5.1M
Copolymer-Based Sarcolemma Stabilization for Protecting Dystrophic Skeletal Muscles in VivoR01AR071349 · NIAMS · UNIVERSITY OF MINNESOTA · PI METZGER, JOSEPH MARK · 2018 to 2022
$2.3M
NHLBI NIH HHS R01 HL122323NIAMS NIH HHS R01 AR071349
6 · The paper itself

Abstract

Poloxamers consisting of poly(ethylene oxide) (PEO) and poly(propylene oxide) segments can protect cell membranes against various forms of stress. We investigated the role of the hydrophobic block chemistry on polymer/membrane binding and cell membrane protection by comparing a series of poly(butylene oxide)-

Indexed as

Ethylene OxidePolyethylene GlycolsAlkenesCytoprotectionEpoxy CompoundsLipidsOxidesPoloxamerPolymersPropylene Glycols1,2-epoxybutaneAlkenesbutyleneEpoxy CompoundsEthylene OxideLipidsOxidesPoloxamerPolyethylene GlycolsPolymersPropylene Glycols

Identifiers

PMID35132851
PMCPMC9093290
OpenAlexW4210840597

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.