Evidence map›Paper›PMID 35137290›Full record

SynthesisObesity surgery2022

Bile Reflux After Single Anastomosis Duodenal-Ileal Bypass with Sleeve (SADI-S): a Meta-analysis of 2,029 Patients.

Ray Portela, Katie Marrerro, Ahmet Vahibe, Carlos Galvani, Helmuth Billy, Barham Abu Dayyeh, Benjamin Clapp, Omar M Ghanem

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Surgical Strategies for the Management of Obesity.Methodist DeBakey cardiovascular journal · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ray PortelaDepartment of Surgery, Mayo Clinic, Rochester, MN, 55905, USA.
Katie MarrerroCarle Foundation Hospital General Surgery Residency, Champaign, IL, USA.
Ahmet VahibeDepartment of Surgery, Mayo Clinic, Rochester, MN, 55905, USA.
Carlos GalvaniDepartment of Surgery, Tulane School of Medicine, New Orleans, LA, USA.
Helmuth BillyVentura Advanced Surgical Associates, Ventura, CA, USA.
Barham Abu DayyehDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, 55905, USA.
Benjamin ClappDepartment of Surgery, Texas Tech HSC Paul Foster School of Medicine, El Paso, TX, USA.
Omar M GhanemDepartment of Surgery, Mayo Clinic, Rochester, MN, 55905, USA. Ghanem.Omar@Mayo.Edu.ORCID http://orcid.org/0000-0003-2459-2621

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSingle anastomosis duodenal-ileal bypass with sleeve (SADI-S) is a novel bariatric surgery modified from the classic biliopancreatic diversion with duodenal switch (BPD-DS). These surgical modifications address most BPD-DS hurdles, but the risk of bile reflux may hinder SADI-S acceptance. We aimed to evaluate the event rate of bile reflux after SADI-S.

methodsPubMed, ScienceDirect, Cochrane, Web of Science, and Google Scholar were used to search English articles between 2008 and 2021 by two independent reviewers using the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). The risk of bias was assessed using Newcastle-Ottawa Scale and the JBI tool. Event rates were meta-analyzed using Comprehensive Meta-Analysis (CME) V3.

resultsOut of 3,027 studies analyzed, seven were included. Studies were published between 2010 and 2020. Six out of 7 studies were retrospective. Three studies had a low risk of bias, three studies had a moderate risk of bias, and one had a high risk of bias. The mean follow-up was 10.3 months. The total number of patients was 2,029, with 25 reports of bile reflux, resulting in an incidence of 1.23%, with an event rate of 0.016 (95% CI 0.004 to 0.055).

conclusionsBile reflux has not been demonstrated to be problematic after SADI-S in this meta-analysis. Further long-term studies are needed.

Indexed as

Bile RefluxBiliopancreatic DiversionGastric BypassObesity, MorbidAnastomosis, SurgicalDuodenumGastrectomyHumansRetrospective StudiesMeta-analysisObesitySADI-SSingle anastomosis duodenal-ileal bypass with sleeveSystematic review

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.