Evidence map›Paper›PMID 35137789›Full record

SynthesisArquivos brasileiros de cardiologia2022

Schistosomiasis & Heart - On Behalf of the Neglected Tropical Diseases and other Infectious Diseases affecting the Heart (the NET-Heart Project).

Edith Liliana Posada-Martínez, Luis Gerardo Gonzalez-Barrera, Kiera Liblik, Juan Esteban Gomez-Mesa, Clara Saldarriaga, Juan Maria Farina, Josefina Parodi, Zier Zhou, Manuel Martinez-Selles, Adrian Baranchuk

Open access · diamondAbstract readSystematic Review
In one paragraph

Synthesis in Arquivos brasileiros de cardiologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. IL-6 and TGF-β1 as biomarkers of schistosomiasis-associated pulmonary hypertension in a murine model.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  2. Parasitic lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 6 countries.

Edith Liliana Posada-MartínezIgnacio Chavez National Institute for Cardiology - Echocardiography, Juan Badiano - México.ORCID 0000-0002-3749-4281
Luis Gerardo Gonzalez-BarreraMedical Society of 20 of November National Medical Center - Cardiology, Mexico City - México.ORCID 0000-0001-8472-9509
Kiera LiblikQueen's University, Kingston, Ontario - Canadá.
Juan Esteban Gomez-MesaValle del Lili Foundation Internal Medicine Department, Valle del Cauca - Colômbia.ORCID 0000-0002-6635-6224
Clara SaldarriagaCardiovascular Clinic Santa Maria - Cardiology and Heart Failure, Medellin - Colômbia.
Juan Maria FarinaClinica Olivos - Cardiology, Buenos Aires - Argentina.ORCID 0000-0002-5824-8485
Josefina ParodiCardiovascular Institute of Buenos Aires, Buenos Aires - Argentina.
Zier ZhouQueen's University, Kingston, Ontario - Canadá.
Manuel Martinez-SellesGregorio Maranon General University Hospital Cardiology Service, Madrid - Espanha.
Adrian BaranchukQueen's University, Kingston, Ontario - Canadá.
Queen's University · CAFundación Valle del Lili · COHospital General Universitario Gregorio Marañón · ESInstituto de Efectividad Clínica y Sanitaria · ARInstituto Nacional de Cardiología · MXInstituto Tecnológico de Buenos Aires (ITBA) · ARResearch Medical Center · USUniversidad de Antioquia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSchistosomiasis is a Neglected Tropical Disease which may lead to cardiovascular (CV) complications. However, the CV involvement in schistosomiasis has yet to be fully elucidated due to the limited number of cases and lack of reliable evidence, as schistosomiasis typically occurs in locations without adequate infrastructure for robust data collection.

objectiveThis systematic review aims to assess cardiovascular implications of schistosomiasis, including in the diagnosis and treatment, and propose an algorithm for screening of CV manifestations.

methodsA systematic review was performed in the MEDLINE/PubMed and LILACS databases of articles on the CV involvement in schistosomiasis.

resultsThirty-three records were considered for this review: six review articles, one systematic review, one clinical trial, 14 observational studies, seven case reports, and four cases series. CV involvement includes a wide spectrum of clinical conditions, such as myocardial ischemia, ventricular dysfunction, myocarditis, pulmonary arterial hypertension, and pericarditis.

conclusionsCardiac complications of schistosomiasis may cause long-term disability and death. Clinical monitoring, physical examination, early electrocardiogram, and echocardiogram should be considered as key measures to detect CV involvement. Due to the lack of effective treatment of complications, sanitation and education in endemic areas are necessary for the elimination of this global health problem.

Indexed as

Communicable DiseasesHeart DiseasesMyocarditisSchistosomiasisHeartHumansNeglected DiseasesObservational Studies as Topic

Identifiers

PMID35137789
PMCPMC9368866
OpenAlexW3217765909

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.