Evidence map›Paper›PMID 35138681›Full record

SynthesisJournal of internal medicine2022

Ambient air pollution and cardiovascular diseases: An umbrella review of systematic reviews and meta-analyses.

Jeroen de Bont, Suganthi Jaganathan, Marcus Dahlquist, Åsa Persson, Massimo Stafoggia, Petter Ljungman

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Journal of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 238 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
238citing papers in PubMed, 14 pooled it
51.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

238 citing papers in PubMed, 14 syntheses or guidelines pooled it, 512 citations in OpenAlex.

  1. The Indoor Microbiome: Sampling, Analysis and Emerging Trends.Environmental microbiology reports · 2026
    Pooled it
  2. Association between PMBMC public health · 2026
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178 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Jeroen de BontInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-9924-5961
Suganthi JaganathanInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Marcus DahlquistInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Åsa PerssonInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Massimo StafoggiaInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Petter LjungmanInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-7815-2632
Karolinska Institutet · SEDanderyds sjukhus · SE

Funding

Air Pollution and Health GEOHealth Hub Research and Capacity Building ProgramU01TW010097 · FIC · PUBLIC HEALTH FOUNDATION OF INDIA · PI Dorairaj Prabhakaran, Poornima Prabhakaran · 2015 to 2026
$3.1M
FIC NIH HHS U01 TW010097
6 · The paper itself

Abstract

The available evidence on the effects of ambient air pollution on cardiovascular diseases (CVDs) has increased substantially. In this umbrella review, we summarized the current epidemiological evidence from systematic reviews and meta-analyses linking ambient air pollution and CVDs, with a focus on geographical differences and vulnerable subpopulations. We performed a search strategy through multiple databases including articles between 2010 and 31 January 2021. We performed a quality assessment and evaluated the strength of evidence. Of the 56 included reviews, the most studied outcomes were stroke (22 reviews), all-cause CVD mortality, and morbidity (19). The strongest evidence was found between higher short- and long-term ambient air pollution exposure and all-cause CVD mortality and morbidity, stroke, blood pressure, and ischemic heart diseases (IHD). Short-term exposures to particulate matter <2.5 μm (PM

Indexed as

Air PollutantsAir PollutionCardiovascular DiseasesHypertensionMyocardial InfarctionStrokeAgedEnvironmental ExposureHumansParticulate MatterSystematic Reviews as TopicAir PollutantsParticulate Matterambient air pollutioncardiovascular diseasesnitrogen oxidesparticulate matterumbrella review

Identifiers

PMID35138681
PMCPMC9310863
OpenAlexW4210946742

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.