ArticlePloS one2022
A scoping review of the contralateral effects of unilateral peripheral stimulation on neuromuscular function.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Revisiting the stretch-induced force deficit: A systematic review with multilevel meta-analysis of acute effects.Journal of sport and health science · 2024Pooled it
- Acute and chronic effects of stretching on balance: a systematic review with multilevel meta-analysis.Frontiers in medicine · 2024Pooled it
- Cross-Education of Strength: From Theory to Practice in Contemporary Sports Rehabilitation-A Narrative Review and Clinical Implications.Sports medicine - open · 2025Review
- Cross-limb transfer during isometric plantar flexion familiarization.Scientific reports · 2025Article
- Stable improvement in hand muscle strength in incomplete spinal cord injury patients by long-term paired associative stimulation-a case series study.Frontiers in neurology · 2025Article
- Focal muscle vibration and action observation: a combined approach for muscle strengthening.European journal of translational myology · 2024Article
- Comparison of Supervised versus Self-Administered Stretching on Bench Press Maximal Strength and Force Development.Sports (Basel, Switzerland) · 2024Article
- Effects of Unilateral Neuromuscular Electrical Stimulation with Illusionary Mirror Visual Feedback on the Contralateral Muscle: A Pilot Study.International journal of environmental research and public health · 2023Article
- A novel balance training approach: Biomechanical study of virtual reality-based skateboarding.Frontiers in bioengineering and biotechnology · 2023Article
- Influence of One Hour versus Two Hours of Daily Static Stretching for Six Weeks Using a Calf-Muscle-Stretching Orthosis on Maximal Strength.International journal of environmental research and public health · 2022Article
- Sex differences in stretch-induced hypertrophy, maximal strength and flexibility gains.Frontiers in physiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is known that resistance exercise using one limb can affect motor function of both the exercised limb and the unexercised contralateral limb, a phenomenon termed cross-education. It has been suggested that cross-education has clinical implications, e.g. in rehabilitation for orthopaedic conditions or post-stroke paresis. Much of the research on the contralateral effect of unilateral intervention on motor output is based on voluntary exercise. This scoping review aimed to map the characteristics of current literature on the cross-education caused by three most frequently utilised peripheral neuromuscular stimulation modalities in this context: electrical stimulation, mechanical vibration and percutaneous needling, that may direct future research and translate to clinical practice. A systematic search of relevant databases (Ebsco, ProQuest, PubMed, Scopus, Web of Science) through to the end of 2020 was conducted following the PRISMA Extension for Scoping Review. Empirical studies on human participants that applied a unilateral peripheral neuromuscular stimulation and assessed neuromuscular function of the stimulated and/or the unstimulated side were selected. By reading the full text, the demographic characteristics, context, design, methods and major findings of the studies were synthesised. The results found that 83 studies were eligible for the review, with the majority (53) utilised electrical stimulation whilst those applied vibration (18) or needling (12) were emerging. Although the contralateral effects appeared to be robust, only 31 studies claimed to be in the context of cross-education, and 25 investigated on clinical patients. The underlying mechanism for the contralateral effects induced by unilateral peripheral stimulation remains unclear. The findings suggest a need to enhance the awareness of cross-education caused by peripheral stimulation, to help improve the translation of theoretical concepts to clinical practice, and aid in developing well-designed clinical trials to determine the efficacy of cross-education therapies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.