Evidence map›Paper›PMID 35144641›Full record

ArticleRadiation oncology (London, England)2022

A feasibility study for in vivo treatment verification of IMRT using Monte Carlo dose calculation and deep learning-based modelling of EPID detector response.

Jun Zhang, Zhibiao Cheng, Ziting Fan, Qilin Zhang, Xile Zhang, Ruijie Yang, Junhai Wen

Abstract read
In one paragraph

Article in Radiation oncology (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jun ZhangDepartment of Biomedical Engineering, School of Life Science, Beijing Institute of Technology, Beijing, China. 284614835@qq.com.ORCID http://orcid.org/0000-0002-9496-9845
Zhibiao ChengDepartment of Biomedical Engineering, School of Life Science, Beijing Institute of Technology, Beijing, China.
Ziting FanDepartment of Biomedical Engineering, School of Life Science, Beijing Institute of Technology, Beijing, China.
Qilin ZhangDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.
Xile ZhangDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.
Ruijie YangDepartment of Radiation Oncology, Peking University Third Hospital, Beijing, China.
Junhai WenDepartment of Biomedical Engineering, School of Life Science, Beijing Institute of Technology, Beijing, China. wenjh@bit.edu.cn.

Funding

Beijing Municipal Commission of science and technology collaborative innovation project Z201100005620012Capital's Funds for Health Improvement and Research 2020-2Z-40919National Key R&D Program of China 2016YFC0105104National Key Research and Development Program of China 2021YFE0202500NSAF No. U1830126
6 · The paper itself

Abstract

backgroundThis paper describes the development of a predicted electronic portal imaging device (EPID) transmission image (TI) using Monte Carlo (MC) and deep learning (DL). The measured and predicted TI were compared for two-dimensional in vivo radiotherapy treatment verification.

methodsThe plan CT was pre-processed and combined with solid water and then imported into PRIMO. The MC method was used to calculate the dose distribution of the combined CT. The U-net neural network-based deep learning model was trained to predict EPID TI based on the dose distribution of solid water calculated by PRIMO. The predicted TI was compared with the measured TI for two-dimensional in vivo treatment verification.

resultsThe EPID TI of 1500 IMRT fields were acquired, among which 1200, 150, and 150 fields were used as the training set, the validation set, and the test set, respectively. A comparison of the predicted and measured TI was carried out using global gamma analyses of 3%/3 mm and 2%/2 mm (5% threshold) to validate the model's accuracy. The gamma pass rates were greater than 96.7% and 92.3%, and the mean gamma values were 0.21 and 0.32, respectively.

conclusionsOur method facilitates the modelling process more easily and increases the calculation accuracy when using the MC algorithm to simulate the EPID response, and has potential to be used for in vivo treatment verification in the clinic.

Indexed as

AlgorithmsDeep LearningMonte Carlo MethodPhantoms, ImagingRadiotherapy, Intensity-ModulatedComputer SimulationFeasibility StudiesHumansRadiotherapy DosageDeep learningEPIDIn vivo verificationMonte CarloPRIMO

Identifiers

PMID35144641
PMCPMC8832691

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.