Evidence map›Paper›PMID 35152985›Full record

ReviewCurrent topics in developmental biology2022

Development of a larval nervous system in the sea urchin.

David R McClay

Abstract readReview
In one paragraph

Review in Current topics in developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
14.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

David R McClayDepartment of Biology, Duke University, Durham, NC, United States. Electronic address: dmcclay@duke.edu.
Duke University · US

Funding

EMBRYONIC CELL RECOGNITION: SPECIFICTY DETERMINANTSR01HD014483 · NICHD · DUKE UNIVERSITY · PI DAVID MCCLAY · 1985 to 2026
$7.3M
NICHD NIH HHS R01 HD014483
6 · The paper itself

Abstract

This review reports recent findings on the specification and patterning of neurons that establish the larval nervous system of the sea urchin embryo. Neurons originate in three regions of the embryo. Perturbation analyses enabled construction of gene regulatory networks controlling the several neural cell types. Many of the mechanisms described reflect shared features of all metazoans and others are conserved among deuterostomes. This nervous system with a very small number of neurons supports the feeding and swimming behaviors of the larva until metamorphosis when an adult nervous system replaces that system.

Indexed as

Gene Expression Regulation, DevelopmentalSea UrchinsAnimalsGene Regulatory NetworksLarvaNervous SystemLarval nervous systemNeuralNeural patterningNeural specificationSea urchin

Identifiers

PMID35152985
PMCPMC9968406
OpenAlexW4211027638

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.