Evidence map›Paper›PMID 35154092›Full record

ArticleFrontiers in immunology2022

Rexinoids Modulate Effector T Cell Expression of Mucosal Homing Markers CCR9 and α4β7 Integrin and Direct Their Migration

Kavita R Manhas, Pamela A Marshall, Carl E Wagner, Peter W Jurutka, Michelle V Mancenido, Hannah Z Debray, Joseph N Blattman

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kavita R ManhasBiodesign Center for Immunotherapy, Vaccines, and Virotherapy, Arizona State University, Tempe, AZ, United States.
Pamela A MarshallSchool of Mathematical and Natural Sciences, Arizona State University West Campus, Glendale, AZ, United States.
Carl E WagnerSchool of Mathematical and Natural Sciences, Arizona State University West Campus, Glendale, AZ, United States.
Peter W JurutkaSchool of Mathematical and Natural Sciences, Arizona State University West Campus, Glendale, AZ, United States.
Michelle V MancenidoSchool of Mathematical and Natural Sciences, Arizona State University West Campus, Glendale, AZ, United States.
Hannah Z DebrayBiodesign Center for Immunotherapy, Vaccines, and Virotherapy, Arizona State University, Tempe, AZ, United States.
Joseph N BlattmanBiodesign Center for Immunotherapy, Vaccines, and Virotherapy, Arizona State University, Tempe, AZ, United States.
Arizona State University · US

Funding

QUANTIFYING THE BALANCE BETWEEN VACCINE-INDUCED T CELL PROTECTION AND PATHOLOGYR01AI110720 · NIAID · EMORY UNIVERSITY · PI ANTIA, RUSTOM NOSHIR · 2014 to 2018
$2.0M
Assessing Novel Rexinoids Developed by Comparative Bioresponse Analysis in an Innovative Mouse Model of Cutaneous T Cell LymphomaR15CA249617 · NCI · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI JURUTKA, PETER W, WAGNER, CARL EDWARD · 2020 to 2020
$484k
Modeling, Synthesis, and Biological Evaluation of Potential RXT Selective AgonistR15CA139364 · NCI · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI WAGNER, CARL EDWARD · 2011 to 2011
$458k
NCI NIH HHS R15 CA139364NCI NIH HHS R15 CA249617NIAID NIH HHS R01 AI110720
6 · The paper itself

Abstract

Altering T cell trafficking to mucosal regions can enhance immune responses towards pathogenic infections and cancers at these sites, leading to better outcomes. All-

Indexed as

AnimalsCell MovementFemaleIntegrinsMiceMice, Inbred BALB CMucous MembraneReceptors, CCRT-LymphocytesTretinoinCC chemokine receptor 9integrin alpha4beta7IntegrinsReceptors, CCRTretinoinmigrationmucosalretinoic acidretinoidrexinoidsT-celltoxicityvitamin A

Identifiers

PMID35154092
PMCPMC8829570
OpenAlexW4210750537

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.