Evidence map›Paper›PMID 35159147›Full record

ArticleCells2022

Evaluation of the Usefulness of Human Adipose-Derived Stem Cell Spheroids Formed Using SphereRing

Atsushi Fuku, Yasuhiko Taki, Yuka Nakamura, Hironori Kitajima, Takashi Takaki, Terutsugu Koya, Ikuhiro Tanida, Kaori Nozaki, Hiroshi Sunami, Hiroaki Hirata and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 1 country.

Atsushi FukuDepartment of Orthopedic Surgery, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.ORCID 0000-0001-7229-4974
Yasuhiko TakiDepartment of Orthopedic Surgery, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Yuka NakamuraMedical Research Institute, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Hironori KitajimaDepartment of Orthopedic Surgery, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Takashi TakakiDivision of Electron Microscopy, Showa University, Tokyo 142-8555, Japan.
Terutsugu KoyaCenter for Regenerative Medicine, Kanazawa Medical University Hospital, Kahoku 920-0293, Ishikawa, Japan.
Ikuhiro TanidaGenome Biotechnology Laboratory, Kanazawa Institute of Technology, Hakusan 924-0838, Ishikawa, Japan.
Kaori NozakiDepartment of Pharmacy, Kanazawa Medical University Hospital, Kahoku 920-0293, Ishikawa, Japan.
Hiroshi SunamiAdvanced Medical Research Center, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nakagami 903-0215, Okinawa, Japan.
Hiroaki HirataDepartment of Orthopedic Surgery, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Yoshiyuki TachiDepartment of Orthopedic Surgery, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Togen MasaujiDepartment of Pharmacy, Kanazawa Medical University Hospital, Kahoku 920-0293, Ishikawa, Japan.
Naoki YamamotoCenter for Clinical Trial and Research Support, Research Promotion and Support Headquarters, Fujita Health University, Toyoake 470-1192, Aichi, Japan.ORCID 0000-0002-9659-3204
Yasuhito IshigakiMedical Research Institute, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.ORCID 0000-0003-1012-8430
Shigetaka ShimodairaCenter for Regenerative Medicine, Kanazawa Medical University Hospital, Kahoku 920-0293, Ishikawa, Japan.ORCID 0000-0002-6612-6912
Yusuke ShimizuDepartment of Plastic and Reconstructive Surgery, Graduate School of Medicine, University of the Ryukyus, Nakagami 903-0215, Okinawa, Japan.
Toru IchisekiDepartment of Orthopedic Surgery, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Ayumi KaneujiDepartment of Orthopedic Surgery, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Satoshi OsawaGenome Biotechnology Laboratory, Kanazawa Institute of Technology, Hakusan 924-0838, Ishikawa, Japan.
Norio KawaharaDepartment of Orthopedic Surgery, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Kanazawa Medical University · JPKanazawa Institute of Technology · JPKanazawa Medical University Hospital · JPUniversity of the Ryukyus · JPFujita Health University · JPShowa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is an irreversible degenerative condition causing bone deformation in the joints and articular cartilage degeneration with chronic pain and impaired movement. Adipose-derived stem cell (ADSC) or crushed adipose tissue injection into the joint cavity reportedly improve knee function and symptoms, including pain. Stem cell spheroids may be promising treatment options due to their anti-inflammatory and enhanced tissue regeneration/repair effects. Herein, to form human ADSC spheroids, we used first SphereRing

Indexed as

Cartilage, ArticularOsteoarthritisAdipose TissueAngiopoietin-Like Protein 2Angiopoietin-like ProteinsCytokinesEndothelial CellsHumansStem CellsSynovial FluidAngiopoietin-Like Protein 2Angiopoietin-like ProteinsANGPTL2 protein, humanCytokinesadipose-derived stem cellcell methodsknee osteoarthritisspheroidsynovial fluid

Identifiers

PMID35159147
PMCPMC8834569
OpenAlexW4205886112

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.