ArticleJournal of clinical medicine2022
Sex-Specific Aspects of Skeletal Muscle Metabolism in the Clinical Context of Intensive Care Unit-Acquired Weakness.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Respiratory muscle dysfunction in mechanical ventilation: a systematic review and meta-analysis of biological mechanisms.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Pooled it
- Sex differences in human skeletal muscle fiber types and the influence of age, physical activity, and muscle group: A systematic review and meta-analysis.Physiological reports · 2025Pooled it
- Rethinking Muscle Wasting in Critical Illness: A Systematic Review and Meta-Analysis of Myofiber Size and Protein Turnover.Critical care medicine · 2026Article
- Body composition-guided protein dosing in critically ill patients: a before-and-after study (PROGRESS-ICU).Critical care (London, England) · 2026Observational
- Muscle mass in critically ill patients: analysis using ultrasound, traditional bioelectrical impedance analysis, and wearable devices: a prospective observational study.European journal of medical research · 2026Article
- Factors Influencing Functional Recovery in People After Chronic Critical Illness During Early Neurological Rehabilitation.Journal of multidisciplinary healthcare · 2026Article
- Evaluating skeletal muscle wasting and weakness in models of critical illness.Clinical science (London, England : 1979) · 2025Review
- Muscle weakness after critical illness: unravelling biological mechanisms and clinical hurdles.Critical care (London, England) · 2025Review
- Which factors are associated with acquired weakness in the ICU? An overview of systematic reviews and meta-analyses.Journal of intensive care · 2024Review
- A scoping review of preclinical intensive care unit-acquired weakness models.Frontiers in physiology · 2024Article
- Mitochondrial Dysfunction in Intensive Care Unit-Acquired Weakness and Critical Illness Myopathy: A Narrative Review.International journal of molecular sciences · 2023Review
- Disintegration of the NuRD Complex in Primary Human Muscle Stem Cells in Critical Illness Myopathy.International journal of molecular sciences · 2023Article
- Post-Intensive Care Syndrome after Critical Illness: An Imperative for Effective Prevention.Journal of clinical medicine · 2022Article
- Correction: Engelhardt et al. Sex-Specific Aspects of Skeletal Muscle Metabolism in the Clinical Context of Intensive Care Unit-Acquired Weakness.Journal of clinical medicine · 2022Article
- [54/m-Muscle weakness and prolonged weaning from mechanical ventilation after peritonitis with septic shock : Preparation course anesthesiological intensive care medicine: case 29].Die Anaesthesiologie · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
(1) Background: Female sex is considered a risk factor for Intensive Care Unit-Acquired Weakness (ICUAW). The aim is to investigate sex-specific aspects of skeletal muscle metabolism in the context of ICUAW. (2) Methods: This is a sex-specific sub-analysis from two prospectively conducted trials examining skeletal muscle metabolism and advanced muscle activating measures in critical illness. Muscle strength was assessed by Medical Research Council Score. The insulin sensitivity index was analyzed by hyperinsulinemic-euglycemic (HE) clamp. Muscular metabolites were studied by microdialysis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.