Evidence map›Paper›PMID 35162283›Full record

ArticleInternational journal of environmental research and public health2022

Early Morphological Changes of the Rectus Femoris Muscle and Deep Fascia in Ullrich Congenital Muscular Dystrophy.

Patrizia Sabatelli, Luciano Merlini, Alberto Di Martino, Vittoria Cenni, Cesare Faldini

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Myopathic Ehlers-Danlos Syndrome (mEDS) Related toInternational journal of molecular sciences · 2025
    Review
  4. Article
  5. Collagen VI in the Musculoskeletal System.International journal of molecular sciences · 2023
    Review
  6. Telocytes inside of the peripheral nervous system - a 3D endoneurial network and putative role in cell communication.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Patrizia SabatelliUnit of Bologna, CNR-Institute of Molecular Genetics "Luigi Luca Cavalli-Sforza", 40136 Bologna, Italy.
Luciano MerliniDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-1108-1198
Alberto Di MartinoDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.
Vittoria CenniUnit of Bologna, CNR-Institute of Molecular Genetics "Luigi Luca Cavalli-Sforza", 40136 Bologna, Italy.ORCID 0000-0001-8062-1840
Cesare FaldiniDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.
Istituto Ortopedico Rizzoli · ITThomas Jefferson University · USUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ullrich congenital muscular dystrophy (UCMD) is a severe form of muscular dystrophy caused by the loss of function of collagen VI, a critical component of the muscle-tendon matrix. Magnetic resonance imaging of UCMD patients' muscles shows a peculiar rim of abnormal signal at the periphery of each muscle, and a relative sparing of the internal part. The mechanism/s involved in the early fat substitution of muscle fiber at the periphery of muscles remain elusive. We studied a muscle biopsy of the rectus femoris/deep fascia (DF) of a 3-year-old UCMD patient, with a homozygous mutation in the

Indexed as

Muscular DystrophiesQuadriceps MuscleChild, PreschoolCollagen Type VIFasciaHumansMuscle, SkeletalMutationSclerosisCollagen Type VIcollagen VIfatty infiltrationmuscle fiber atrophytelocytesUllrich congenital muscular dystrophy

Identifiers

PMID35162283
PMCPMC8834967
OpenAlexW4206901614

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.