Evidence map›Paper›PMID 35163151›Full record

ArticleInternational journal of molecular sciences2022

Benzyl Isothiocyanate Attenuates Inflammasome Activation in

Won Sun Park, Jeonghan Lee, Giyoun Na, SaeGwang Park, Su-Kil Seo, Jung Sik Choi, Won-Kyo Jung, Il-Whan Choi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  7. Multidrug-resistantVirulence · 2025
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  10. Impact of Antimicrobial Resistance ofVeterinary sciences · 2025
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  14. Immunomodulatory Effects and Regulatory Mechanisms of (Journal of agricultural and food chemistry · 2024
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  15. Modeling Host-Pathogen Interactions inInternational journal of molecular sciences · 2024
    Review
  16. A Polysaccharide fromFoods (Basel, Switzerland) · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Won Sun ParkDepartment of Physiology, Kangwon National University School of Medicine, Chuncheon 24341, Korea.
Jeonghan LeeDepartment of Anesthesiology and Pain Medicine, Busan Paik Hospital, Inje University, Busan 47392, Korea.ORCID 0000-0002-4616-0355
Giyoun NaDepartment of Microbiology and Immunology, College of Medicine, Inje University, Busan 47392, Korea.
SaeGwang ParkDepartment of Microbiology and Immunology, College of Medicine, Inje University, Busan 47392, Korea.
Su-Kil SeoDepartment of Microbiology and Immunology, College of Medicine, Inje University, Busan 47392, Korea.
Jung Sik ChoiDepartment of Internal Medicine, Busan Paik Hospital, Inje University, Busan 47392, Korea.
Won-Kyo JungDepartment of Biomedical Engineering, Center for Marine-Integrated Biomedical Technology (BK21 Plus), Pukyong National University, Busan 48513, Korea.ORCID 0000-0002-1615-750X
Il-Whan ChoiDepartment of Microbiology and Immunology, College of Medicine, Inje University, Busan 47392, Korea.ORCID 0000-0003-3958-6937
Inje University · KRInje University Busan Paik Hospital · KRKangwon National University · KRPukyong National University · KR

Funding

Inje University 2017
6 · The paper itself

Abstract

Inflammasomes are a group of intracellular multiprotein platforms that play important roles in immune systems. Benzyl isothiocyanate (BITC) is a constituent of cruciferous plants and has been confirmed to exhibit various biological activities. The modulatory effects of BITC on inflammasome-mediated interleukin (IL)-1β expression and its regulatory mechanisms in

Indexed as

Gene Expression RegulationHumansInflammasomesInterleukin-1betaIsothiocyanatesLipopolysaccharidesMitogen-Activated Protein KinasesNF-kappa BPseudomonas aeruginosaTHP-1 Cellsbenzyl isothiocyanateIL1B protein, humanInflammasomesInterleukin-1betaIsothiocyanatesLipopolysaccharidesMitogen-Activated Protein KinasesNF-kappa Bbenzyl isothiocyanateinflammasomesinterleukin-1βnuclear factor-κBPseudomonas aeruginosaTHP-1 cells

Identifiers

PMID35163151
PMCPMC8835927
OpenAlexW4206916966

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.