Evidence map›Paper›PMID 35164343›Full record

ArticleMolecules (Basel, Switzerland)2022

Ma Sheila M de Jesus, Allan Patrick G Macabeo, John Donnie A Ramos, Von Novi O de Leon, Kaori Asamitsu, Takashi Okamoto

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Globospiramine fromCells · 2024
    Article
  5. Article
  6. Correction: de Jesus et al.Molecules (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ma Sheila M de JesusThe Graduate School, University of Santo Tomas, España Blvd., Manila 1015, Philippines.ORCID 0000-0001-7639-3232
Allan Patrick G MacabeoLaboratory for Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for Natural and Applied Sciences, University of Santo Tomas, España Blvd., Manila 1015, Philippines.ORCID 0000-0001-7972-106X
John Donnie A RamosThe Graduate School, University of Santo Tomas, España Blvd., Manila 1015, Philippines.ORCID 0000-0002-1404-4093
Von Novi O de LeonDepartment of Biological Sciences, College of Science, University of Santo Tomas, España Blvd., Manila 1015, Philippines.ORCID 0000-0002-0195-5242
Kaori AsamitsuDepartment of Molecular and Cellular Biology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 4678601, Japan.
Takashi OkamotoDepartment of Molecular and Cellular Biology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 4678601, Japan.
University of Santo Tomas · PHNagoya City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the efficiency in the transcription of the HIV genome contributes to the success of viral replication and infectivity, we investigated the downregulating effects of the spirobisindole alkaloids globospiramine (

Indexed as

AlkaloidsCell LineDose-Response Relationship, DrugHIV-1HIV InfectionsHL-60 CellsHumansI-kappa B KinaseIndole AlkaloidsModels, BiologicalMolecular Docking SimulationNF-kappa BNF-kappa B p50 SubunitPlant ExtractsSignal TransductionSpiro CompoundsAlkaloidsCHUK protein, humandeoxyvobtusineglobospiramineI-kappa B KinaseIndole AlkaloidsNF-kappa BNF-kappa B p50 SubunitNFKB1 protein, humanPlant ExtractsRELA protein, humanSpiro CompoundsTranscription Factor RelATumor Necrosis Factor-alphaanti-HIVglobospiramineHIV latencyNF-ĸBspirobisindole alkaloidsVoacanga globosa

Identifiers

PMID35164343
PMCPMC8840767
OpenAlexW4213125520

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.