ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2022
Twenty-year follow-up of children with obstructive sleep apnea.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Exploring the Relationship between Inhaled Corticosteroid Usage, Asthma Severity, and Sleep-Disordered Breathing: A Systematic Literature Review.Advances in respiratory medicine · 2024Pooled it
- Conceptual growth curves of oropharyngeal soft tissues and craniofacial skeletal structures: clinical implications for pediatric airway management.Sleep & breathing = Schlaf & Atmung · 2026Review
- Mandibular Movement Monitoring in Children With Neurodisability.Pediatric pulmonology · 2026Article
- Understanding Severe Sleep-Disordered Breathing in Down Syndrome: Insights from a Clinical-Polysomnographic Cohort.Journal of clinical medicine · 2026Article
- Associations between REM-related respiratory disturbances, metabolic biomarkers, and memory impairment in pediatric sleep-disordered breathing.Pediatric research · 2026Article
- The Natural History of Obstructive Sleep Apnea: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- The Protective Role of Leptin in Neurological Damage Induced by Chronic Intermittent Hypoxia.Molecular neurobiology · 2025Article
- Polysomnographic Profile and Clinical Phenotypes of Osa in Association with Residual Sleep Apnea in Children.Life (Basel, Switzerland) · 2025Article
- Assessment of Craniofacial Growth Pattern Relative to Respiratory Mandibular Movement and Sleep Characteristics: A Pilot Study.European journal of dentistry · 2025Article
- Article
- Prioritising Polysomnography in Children with Suspected Obstructive Sleep Apnoea: Key Roles of Symptom Onset and Sleep Questionnaire Scores.Children (Basel, Switzerland) · 2024Article
- Relationship between size of pharyngeal and palatine tonsils and apnea-hypopnea index in pediatric obstructive sleep apnea.Fujita medical journal · 2024Article
- Sleep Disordered Breathing in Children with Autism Spectrum Disorder: An In-Depth Review of Correlations and Complexities.Children (Basel, Switzerland) · 2023Review
- Associations between body mass index, sleep-disordered breathing, brain structure, and behavior in healthy children.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Predictive Power of Oxygen Desaturation Index (ODI) and Apnea-Hypopnea Index (AHI) in Detecting Long-Term Neurocognitive and Psychosocial Outcomes of Sleep-Disordered Breathing in Children: A Questionnaire-Based Study.Journal of clinical medicine · 2023Article
- Common sleep disorders in children: assessment and treatment.Neurosciences (Riyadh, Saudi Arabia) · 2023Review
- Is There an Association between Viral Infections and Risk for Pediatric Obstructive Sleep Apnea? A Systematic Review.Children (Basel, Switzerland) · 2023Review
- Clinical Characteristics Combined with Craniofacial Photographic Analysis in Children with Obstructive Sleep Apnea.Nature and science of sleep · 2023Article
- Cluster Analysis of Home Polygraphic Recordings in Symptomatic Habitually-Snoring Children: A Precision Medicine Perspective.Journal of clinical medicine · 2022Article
- Pediatric Sleep-Disordered Breathing and Long-Term Complications: Clinical and Health Implications.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesObstructive sleep apnea (OSA) in children is associated with acute metabolic, cardiovascular, and neurocognitive abnormalities. The long-term outcomes of childhood OSA into adulthood have not been established. We performed a 20-year follow-up of patients with polysomnography-documented OSA in childhood compared to a healthy control group to evaluate the long-term anthropometric, sleep, cognitive, and cardiovascular outcomes.
methodsChildren diagnosed with severe OSA between ages 1 and 17 years (mean, 4.87 ± 2.77) were prospectively contacted by telephone as young adults after approximately 20 years. Data collected included reported anthropometric information, educational level, health history, and Berlin questionnaire scores.
resultsYoung adults with confirmed severe OSA in childhood had significantly higher adulthood body mass index (
conclusionsAdults with a history of severe childhood OSA have a high risk of snoring, elevated body mass index, and lower academic achievement in adulthood. Thus, children with severe OSA may be at increased risk of chronic diseases later in life. The intervening coronavirus disease 2019 (COVID-19) pandemic has introduced considerable additional neurobehavioral morbidity complicating the identification of the full long-term consequences of childhood OSA. CITATION: Nosetti L, Zaffanello M, Katz ES, et al. Twenty-year follow-up of children with obstructive sleep apnea.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.