Evidence map›Paper›PMID 35165105›Full record

Trial reportBMJ open2022

Process evaluation of peer-to-peer delivery of HIV self-testing and sexual health information to support HIV prevention among youth in rural KwaZulu-Natal, South Africa: qualitative analysis.

Oluwafemi Atanda Adeagbo, Janet Seeley, Dumsani Gumede, Sibongiseni Xulu, Nondumiso Dlamini, Manono Luthuli, Jaco Dreyer, Carina Herbst, F Cowan, Natsayi Chimbindi and 9 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 10 institutions in 9 countries.

Oluwafemi Atanda AdeagboDepartment of Health Promotion, Education & Behaviour, University of South Carolina Arnold School of Public Health, Columbia, South Carolina, USA oadeagbo@mailbox.sc.edu.ORCID 0000-0003-1462-9275
Janet SeeleySocial Science & Research Ethics Unit, Africa Health Research Institute, Durban, South Africa.ORCID 0000-0002-0583-5272
Dumsani GumedeSocial Science & Research Ethics Unit, Africa Health Research Institute, Durban, South Africa.
Sibongiseni XuluSocial Science & Research Ethics Unit, Africa Health Research Institute, Durban, South Africa.
Nondumiso DlaminiSocial Science & Research Ethics Unit, Africa Health Research Institute, Durban, South Africa.
Manono LuthuliSocial Science & Research Ethics Unit, Africa Health Research Institute, Durban, South Africa.
Jaco DreyerSocial Science & Research Ethics Unit, Africa Health Research Institute, Durban, South Africa.
Carina HerbstSocial Science & Research Ethics Unit, Africa Health Research Institute, Durban, South Africa.
F CowanInternational Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.ORCID 0000-0003-3087-4422
Natsayi ChimbindiSocial Science & Research Ethics Unit, Africa Health Research Institute, Durban, South Africa.
Karin HatzoldPopulation Services International, Harare, Zimbabwe.
Nonhlanhla OkesolaSocial Science & Research Ethics Unit, Africa Health Research Institute, Durban, South Africa.
Cheryl JohnsonDepartment of HIV/AIDS, World Health Organization, Geneva, Switzerland.
Guy HarlingSocial Science & Research Ethics Unit, Africa Health Research Institute, Durban, South Africa.ORCID 0000-0001-6604-491X
Hasina SubedarNational Department of Health, Pretoria, South Africa.
Lorraine SherrUniversity College London Faculty of Population Health Sciences, London, UK.
Nuala McGrathFaculty of Social, Human and Mathematical Sciences, University of Southampton, Southampton, UK.
Liz CorbettInfectious and Tropical Diseases, LSHTM, London, UK.
Maryam ShahmaneshSocial Science & Research Ethics Unit, Africa Health Research Institute, Durban, South Africa.
Africa Health Research Institute · ZACenter for Global Development · USHarvard University · USInternational Center for Public Health · USLondon School of Hygiene & Tropical Medicine · GBNational Department of Health · PGUniversity College London · GBUniversity of Southampton · GBUniversity of South Carolina · USWorld Health Organization - Pakistan · PK

Funding

Maximizing combination HIV prevention, uptake and retention by adolescent girls and young womenR01MH114560 · NIMH · KWAZULU-NATAL RESEARCH INSTITUTE TB-HIV · PI SHAHMANESH, MARYAM · 2017 to 2023
$2.0M
NIMH NIH HHS R01 MH114560Wellcome TrustWorld Health Organization 001
6 · The paper itself

Abstract

objectivePeer-to-peer (PTP) HIV self-testing (HIVST) distribution models can increase uptake of HIV testing and potentially create demand for HIV treatment and pre-exposure prophylaxis (PrEP). We describe the acceptability and experiences of young women and men participating in a cluster randomised trial of PTP HIVST distribution and antiretroviral/PrEP promotion in rural KwaZulu-Natal.

methodsBetween March and September 2019, 24 pairs of trained peer navigators were randomised to two approaches to distribute HIVST packs (kits+HIV prevention information):

resultsOverall, PTP approaches were acceptable and valued by young people. Participants were comfortable sharing sexual health issues they would not share with adults. Coupled with HIVST, peer (friends) support facilitated HIV testing and solidarity for HIV status disclosure and treatment. However, some young people showed limited interest in other sexual health information provided. Some young people were wary of receiving health information from friends perceived as non-professionals while others avoided sharing personal issues with peer navigators from their community. Referral slips and youth-friendly clinics were facilitators to PrEP uptake. Family disapproval, limited information, daily pills and perceived risks were major barriers to PrEP uptake.

conclusionBoth professional (peer navigators) and social network (friends) approaches were acceptable methods to receive HIVST and sexual health information. Doubts about the professionalism of friends and overly exclusive focus on HIVST information materials may in part explain why HIVST kits, without peer navigators support, did not create demand for PrEP.

Indexed as

HIV InfectionsSexual HealthAdolescentAdultFemaleHIV TestingHumansMaleSelf-TestingSouth AfricaYoung Adulthealth & safetyHIV & AIDSpublic health

Identifiers

PMID35165105
PMCPMC8845207
OpenAlexW4213125559

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.