Evidence map›Paper›PMID 35166177›Full record

ArticleRenal failure2022

Machine learning for the prediction of acute kidney injury in critical care patients with acute cerebrovascular disease.

Xiaohong Zhang, Siying Chen, Kunmei Lai, Zhimin Chen, Jianxin Wan, Yanfang Xu

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiaohong ZhangDepartment of Nephrology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Siying ChenDepartment of Nephrology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Kunmei LaiDepartment of Nephrology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Zhimin ChenDepartment of Nephrology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Jianxin WanDepartment of Nephrology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Yanfang XuDepartment of Nephrology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Fujian Medical University · CNFirst Affiliated Hospital of Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAcute kidney injury (AKI) is a common complication and associated with a poor clinical outcome. In this study, we developed and validated a model for predicting the risk of AKI through machine learning methods in critical care patients with acute cerebrovascular disease.

methodsThis study was a retrospective study based on two different cohorts. Five machine learning methods were used to develop AKI risk prediction models. We used six popular metrics (AUROC, F2-Score, accuracy, sensitivity, specificity and precision) to evaluate the performance of these models.

resultsWe identified 2935 patients in the MIMIC-III database and 499 patients in our local database to develop and validate the AKI risk prediction model. The incidence of AKI in these two different cohorts was 18.3% and 61.7%, respectively. Analysis showed that several laboratory parameters (serum creatinine, hemoglobin, white blood cell count, bicarbonate, blood urea nitrogen, sodium, albumin, and platelet count), age, and length of hospital stay, were the top ten important factors associated with AKI. The analysis demonstrated that the XGBoost had higher AUROC (0.880, 95%CI: 0.831-0.929), indicating that the XGBoost model was better at predicting AKI risk in patients with acute cerebrovascular disease than other models.

conclusionsThis study developed machine learning methods to identify critically ill patients with acute cerebrovascular disease who are at a high risk of developing AKI. This result suggested that machine learning techniques had the potential to improve the prediction of AKI risk models in critical care.

Indexed as

Machine LearningAcute Kidney InjuryAgedCerebrovascular DisordersChinaCritical CareDatabases, FactualFemaleHumansLogistic ModelsMaleMiddle AgedOrgan Dysfunction ScoresRetrospective StudiesROC Curveacute cerebrovascular diseaseAcute kidney injurymachine learning methodsrisk prediction models

Identifiers

PMID35166177
PMCPMC8856083
OpenAlexW4213035382

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.