SynthesisAlimentary pharmacology & therapeutics2022
Systematic review: development of a consensus code set to identify cirrhosis in electronic health records.
Synthesis in Alimentary pharmacology & therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review: development of a consensus code set to identify cirrhosis in electronic health records.Alimentary pharmacology & therapeutics · 2022Pooled it
- Article
- Socioeconomic factors and SGLT2 inhibitor initiation in patients with heart failure-a claims data analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Clinical Outcomes in Patients with Primary Sclerosing Cholangitis With and Without Inflammatory Bowel Disease.Digestive diseases and sciences · 2026Article
- Development and evaluation of a hybrid algorithm for identifying hospitalized patients with cirrhosis.Canadian liver journal · 2026Article
- Article
- Safety and effectiveness of phenobarbital vs. benzodiazepines for severe alcohol withdrawal in alcohol-associated liver disease in the ICU.JHEP reports : innovation in hepatology · 2026Article
- Identifying subjects at risk of liver cirrhosis via a range of thresholds for common fibrosis markers: A Welsh general population-based cohort study.Journal of internal medicine · 2026Article
- Accurately identifying cirrhosis and its complications to create the novel statewide Indiana digital cirrhosis registry.Scientific reports · 2026Article
- Plasma IGFBP7 improves risk reclassification for liver-related outcomes: Insights from proteo-transcriptomic profiling.JHEP reports : innovation in hepatology · 2026Article
- Interpretable model for early prediction of 28-day mortality in patients with cirrhosis and sepsis: a multi-cohort ICU study.BMC gastroenterology · 2026Article
- High Hospitalization Rates and Risk Factors Among Frail Patients With Cirrhosis: A 10-year Population-based Cohort Study.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2025Article
- Cirrhosis epidemiology in Denmark 1998-2022, and 2030 forecast.JHEP reports : innovation in hepatology · 2025Article
- Identifying emergency presentations of chronic liver disease using routinely collected administrative hospital data.JHEP reports : innovation in hepatology · 2025Article
- Validation of ICD-10 Consensus Code Set for Cirrhosis Detection Using Electronic Health Records in an Asian Population.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Clinical Ethics Consultations in Cirrhosis Care.Digestive diseases and sciences · 2025Article
- Contrasting rule and machine learning based digital self triage systems in the USA.NPJ digital medicine · 2024Review
- A roadmap for clinical trials in MASH-related compensated cirrhosis.Nature reviews. Gastroenterology & hepatology · 2024Review
- Estimating the economic impact of comorbidities in patients with MASH and defining high-cost burden in patients with noncirrhotic MASH.Hepatology communications · 2024Observational
- Validating new coding algorithms to improve identification of alcohol-associated and nonalcohol-associated cirrhosis hospitalizations in administrative databases.Hepatology communications · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundElectronic health records (EHRs) collate longitudinal data that can be used to facilitate large-scale research in patients with cirrhosis. However, there is no consensus code set to define the presence of cirrhosis in EHR. This systematic review aims to evaluate the validity of diagnostic coding in cirrhosis and to synthesise a comprehensive set of ICD-10 codes for future EHR research.
methodMEDLINE and EMBASE databases were searched for studies that used EHR to identify cirrhosis and cirrhosis-related complications. Validated code sets were summarised, and the performance characteristics were extracted. Citation analysis was done to inform development of a consensus code set. This was then validated in a cohort of patients.
resultsOne thousand six hundred twenty-six records were screened, and 18 studies were identified. The positive predictive value (PPV) was the most frequently reported statistical estimate and was ≥80% in 17/18 studies. Citation analyses showed continued variation in those used in contemporary research practice. Nine codes were identified as those most frequently used in the literature and these formed the consensus code set. This was validated in diverse patient populations from Europe and North America and showed high PPV (83%-89%) and greater sensitivity for the identification of cirrhosis than the most often used code set in the recent literature.
conclusionThere is variation in code sets used to identify cirrhosis in contemporary research practice. A consensus set has been developed and validated, showing improved performance, and is proposed to align EHR study designs in cirrhosis to facilitate international collaboration and comparisons.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.