Evidence map›Paper›PMID 35166581›Full record

ArticleNucleic acid therapeutics2022

Exon Skipping Through Chimeric Antisense

Giuseppina Covello, Gehan H Ibrahim, Niccolò Bacchi, Simona Casarosa, Michela Alessandra Denti

Open access · hybridAbstract read
In one paragraph

Article in Nucleic acid therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Retinitis pigmentosa GTPase regulator-related retinopathy and gene therapy.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Giuseppina CovelloRNA Biology and Biotechnology Laboratory, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy.ORCID 0000-0001-5660-8283
Gehan H IbrahimDepartment of Medical Biochemistry, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.ORCID 0000-0003-1586-6395
Niccolò BacchiRNA Biology and Biotechnology Laboratory, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy.
Simona CasarosaNeural Development and Regeneration Laboratory, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy.ORCID 0000-0002-7744-8183
Michela Alessandra DentiRNA Biology and Biotechnology Laboratory, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy.ORCID 0000-0001-7203-7062
University of Trento · ITSuez Canal University · EGUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inherited retinal dystrophies are caused by mutations in more than 250 genes, each of them carrying several types of mutations that can lead to different clinical phenotypes. Mutations in

Indexed as

Eye ProteinsRetinitis PigmentosaExonsGTP PhosphohydrolasesHumansMutationRNA, Small NuclearEye ProteinsGTP PhosphohydrolasesRNA, Small NuclearRPGR protein, humanU1 small nuclear RNAalternative splicingexon skippingRetinitis Pigmentosa GTPase-regulator (RPGR)RNA TherapeuticsU1 snRNA

Identifiers

PMID35166581
PMCPMC9416563
OpenAlexW4212780988

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.