Evidence map›Paper›PMID 35168996›Full record

ArticleRNA (New York, N.Y.)2022

Identification and mapping of post-transcriptional modifications on the HIV-1 antisense transcript

Mariana Estevez, Rui Li, Biplab Paul, Kaveh Daneshvar, Alan C Mullen, Fabio Romerio, Balasubrahmanyam Addepalli

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. FAIR Omics Data Management: Overview, Challenges, and Best Practices.Advances in experimental medicine and biology · 2026
    Review
  3. Article
  4. Review
  5. Biomedical engineering and computational biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mariana Estevez *Department of Chemistry, University of Cincinnati, Cincinnati, Ohio 45221, USA.
Rui Li *Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
Biplab PaulMassachusetts General Hospital, Boston, Massachusetts 02114, USA.
Kaveh DaneshvarMassachusetts General Hospital, Boston, Massachusetts 02114, USA.
Alan C MullenMassachusetts General Hospital, Boston, Massachusetts 02114, USA.
Fabio RomerioDepartment of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
Balasubrahmanyam AddepalliDepartment of Chemistry, University of Cincinnati, Cincinnati, Ohio 45221, USA.

Funding

Sustained HIV Remission via Sequence-Specific Epigenetic Silencing of Latent ProvirusesR01AI144983 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI ROMERIO, FABIO · 2019 to 2024
$3.6M
NIAID NIH HHS R01 AI144983
6 · The paper itself

Abstract

The human immunodeficiency virus type 1 (HIV-1) encodes multiple RNA molecules. Transcripts that originate from the proviral 5' long terminal repeat (LTR) function as messenger RNAs for the expression of 16 different mature viral proteins. In addition, HIV-1 expresses an antisense transcript (

Indexed as

HIV-1Chromatography, LiquidHumansNucleosidesRNA, AntisenseRNA Processing, Post-TranscriptionalTerminal Repeat SequencesNucleosidesRNA, Antisenseantisense RNAepitranscriptomicsHIV-1nucleoside analysisRNA modification mapping

Identifiers

PMID35168996
PMCPMC9014878

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.