ArticleCell reports2022
Distinct MUNC lncRNA structural domains regulate transcription of different promyogenic factors.
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Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24citing papers in PubMed
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Who cites it
24 citing papers in PubMed.
- Pnky lncRNA secondary structure maps identify functional regions that control neurogenesis in neural stem cells.Cell reports · 2026Article
- Robust mammalian RNA localization elements are complex and multipartite.bioRxiv : the preprint server for biology · 2026Article
- Review
- Deciphering the regulatory landscape of enhancer RNAs in health and disease.Signal transduction and targeted therapy · 2026Review
- Decoding the lncRNA World: Comprehensive Approaches to lncRNA Structure and Interactome Studies.Cells · 2026Review
- SHAPE-Based Chemical Probes for Studying preQACS chemical biology · 2025Article
- LncRNA SChLAP1 Promotes Cancer Cell Proliferation and Invasion Via Its Distinct Structural Domains and Conserved Regions.Journal of molecular biology · 2025Article
- Structural basis for the function of long noncoding RNAbioRxiv : the preprint server for biology · 2025Article
- Structural analysis of the lncRNA SChLAP1 reveals protein binding interfaces and a conformationally heterogenous retroviral insertion.RNA (New York, N.Y.) · 2025Article
- Biomolecules Interacting with Long Noncoding RNAs.Biology · 2025Review
- Template switching enables chemical probing of native RNA structures.RNA (New York, N.Y.) · 2024Article
- Functional Validation of SAM Riboswitch Element A fromBiochemistry · 2024Article
- Calorie restriction and rapamycin distinctly restore non-canonical ORF translation in the muscles of aging mice.NPJ Regenerative medicine · 2024Article
- The Function and Regulation Mechanism of Non-Coding RNAs in Muscle Development.International journal of molecular sciences · 2023Review
- A signature of cuproptosis-related lncRNAs predicts prognosis and provides basis for future anti-tumor drug development in breast cancer.Translational cancer research · 2023Article
- Distinct regulatory functions and biological roles of lncRNA splice variants.Molecular therapy. Nucleic acids · 2023Review
- Enhancer RNAs in transcriptional regulation: recent insights.Frontiers in cell and developmental biology · 2023Review
- Context-Dependent Function of Long Noncoding RNAMolecular and cellular biology · 2022Article
- Enhancer RNAs step forward: new insights into enhancer function.Development (Cambridge, England) · 2022Article
- Lnc-EST12, which is negatively regulated by mycobacterial EST12, suppresses antimycobacterial innate immunity through its interaction with FUBP3.Cellular & molecular immunology · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Roza K PrzanowskaDepartment of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Department of Biomedical Engineering, University of Virginia School of Engineering, Charlottesville, VA 22908, USA.
Chase A WeidmannDepartment of Chemistry, University of North Carolina, Chapel Hill, NC 27599, USA; Department of Biological Chemistry and Center for RNA Biomedicine, University of Michigan Medical School, Ann Arbor, MI 48103, USA.
Shekhar SahaDepartment of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
Magdalena A CichewiczDepartment of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
Kate N JensenDepartment of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
Piotr PrzanowskiDepartment of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Department of Biomedical Engineering, University of Virginia School of Engineering, Charlottesville, VA 22908, USA.
Patrick S IrvingDepartment of Chemistry, University of North Carolina, Chapel Hill, NC 27599, USA.
Kevin A JanesDepartment of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Department of Biomedical Engineering, University of Virginia School of Engineering, Charlottesville, VA 22908, USA.
Michael J GuertinDepartment of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; R. D. Berlin Center for Cell Analysis and Modeling, University of Connecticut, Farmington, CT 06030, USA.
Kevin M WeeksDepartment of Chemistry, University of North Carolina, Chapel Hill, NC 27599, USA.
Anindya DuttaDepartment of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Department of Genetics, University of Alabama, Birmingham, AL 35233, USA. Electronic address: duttaa@uab.edu.
Funding
Discovery and Function of Higher-Order RNA StructureR35GM122532 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Kevin M Weeks · 2017 to 2026
$5.7MMechanisms of coordinate gene regulation by transcription factorsR35GM128635 · NIGMS · UNIVERSITY OF VIRGINIA · PI Michael Joseph Guertin · 2018 to 2026
$3.4MMechanism of action of an lncRNA for directing muscle differentiationR01AR067712 · NIAMS · UNIVERSITY OF VIRGINIA · PI DUTTA, ANINDYA · 2016 to 2020
$1.7MUnraveling the MALAT1 lncRNA-protein interaction networks that drive lung cancer metastasisK22CA262349 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEIDMANN, CHASE A · 2021 to 2023
$486kLong non-coding RNA Heterogeneity in ER + Breast CancerK00CA253732 · NCI · UNIVERSITY OF VIRGINIA · PI PRZANOWSKA, ROZA KAMILA · 2021 to 2024
$400kLong non-coding RNAs as novel therapeutic targets in gliomas treatmentF99CA253732 · NCI · UNIVERSITY OF VIRGINIA · PI PRZANOWSKA, ROZA KAMILA · 2020 to 2020
$36kNCI NIH HHS F99 CA253732NCI NIH HHS K00 CA253732NCI NIH HHS K22 CA262349NIAMS NIH HHS R01 AR067712NIGMS NIH HHS R35 GM122532NIGMS NIH HHS R35 GM128635
Abstract
Many lncRNAs have been discovered using transcriptomic data; however, it is unclear what fraction of lncRNAs is functional and what structural properties affect their phenotype. MUNC lncRNA (also known as
Indexed as
Transcription, GeneticAnimalsBase SequenceCell DifferentiationCell LineFemaleGenomeMiceMuscle DevelopmentMuscle Fibers, SkeletalNucleic Acid ConformationPhenotypeProtein IsoformsRNA, Long NoncodingRNA, MessengerSequence DeletionProtein IsoformsRNA, Long NoncodingRNA, MessengerChIRPdifferentiation(DRR)eRNAlncRNA structure-function studiesMUNC lncRNAmyogenesisSHAPE-MaPskeletal muscles
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.