Evidence map›Paper›PMID 35173404›Full record

ArticleEvolutionary bioinformatics online2020

Inferring Causation in Yeast Gene Association Networks With Kernel Logistic Regression.

Amira Al-Aamri, Kamal Taha, Maher Maalouf, Andrzej Kudlicki, Dirar Homouz

Abstract read
In one paragraph

Article in Evolutionary bioinformatics online, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amira Al-AamriDepartment of Biomedical Engineering, Khalifa University of Science and Technology, Abu Dhabi, UAE.ORCID https://orcid.org/0000-0002-5419-1688
Kamal TahaDepartment of Electrical and Computer Engineering, Khalifa University of Science and Technology, Abu Dhabi, UAE.
Maher MaaloufResearch Center of Digital Supply Chain and Operations, Department of Industrial and Systems Engineering, Khalifa University of Science and Technology, Abu Dhabi, UAE.
Andrzej KudlickiDepartment of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, TX, USA.ORCID https://orcid.org/0000-0001-8158-9600
Dirar HomouzDepartment of Physics, Khalifa University of Science and Technology, Abu Dhabi, UAE.

Funding

UTMB Clinical and Translational Science AwardUL1TR001439 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI URBAN, RANDALL J · 2015 to 2024
$40.0M
Decoding Genome Instability by Combining Accurate Mapping and Predictive ModelingR01GM112131 · NIGMS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI ROWICKA, MAGA MALGORZATA · 2014 to 2023
$3.2M
NCATS NIH HHS UL1 TR001439NIGMS NIH HHS R01 GM112131
6 · The paper itself

Abstract

Computational prediction of gene-gene associations is one of the productive directions in the study of bioinformatics. Many tools are developed to infer the relation between genes using different biological data sources. The association of a pair of genes deduced from the analysis of biological data becomes meaningful when it reflects the directionality and the type of reaction between genes. In this work, we follow another method to construct a causal gene co-expression network while identifying transcription factors in each pair of genes using microarray expression data. We adopt a machine learning technique based on a logistic regression model to tackle the sparsity of the network and to improve the quality of the prediction accuracy. The proposed system classifies each pair of genes into either connected or nonconnected class using the data of the correlation between these genes in the whole

Indexed as

Bioinformaticsgene co-expression networkpredictive modeltranscription factor

Identifiers

PMID35173404
PMCPMC8842452

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.